ZFIN ID: ZDB-GENE-000329-17
Gene Name: homeobox C12b
Gene Symbol: hoxc12b    Nomenclature History

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Previous Name: sb:eu246

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in central nervous system; mesoderm; musculature system; neural rod; and post-vent region. Orthologous to human HOXC12 (homeobox C12).
Genome Resources: Alliance (1),  Gene:58062 (1),  Ensembl(GRCz11):ENSDARG00000103133 (1)
GENE EXPRESSION
All Expression Data: 9 figures from 2 publications
Directly Submitted Expression Data: 7 figures (6 images) from Thisse et al., 2005 [eu246]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17786 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21829 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxc12b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hoxc12b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxc12b-201 (1)    Ensembl 989
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxc12b No data available
    MARKER RELATIONSHIPS
    hoxc12b Encodes: [EST] eu246 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131545 (1) 852 nt
    Genomic GenBank:AF071260 1600 nt
    Polypeptide UniProtKB:A0A0R4IG55 (1) 283 aa
    Sequence Information (all 13)
    ORTHOLOGY for hoxc12b ( Chr: 11 )
    CITATIONS (30)