Gene
fzd8a
- ID
- ZDB-GENE-000328-3
- Name
- frizzled class receptor 8a
- Symbol
- fzd8a Nomenclature History
- Previous Names
-
- fz5
- fz8a
- fzc
- wu:fd02c05
- zfzc
- zg05
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity. Involved in canonical Wnt signaling pathway; eye field cell fate commitment involved in camera-type eye formation; and neurogenesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural keel; and pectoral fin. Orthologous to human FZD8 (frizzled class receptor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65761 (26 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000539 | Frizzled/Smoothened, 7TM |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041776 | Frizzled 8, cysteine-rich domain |
| Family | IPR015526 | Frizzled/secreted frizzled-related protein |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
| Protein | Length | Frizzled 8, cysteine-rich domain | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Frizzled/Smoothened, 7TM | GPCR, family 2-like, 7TM |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9YI00
|
579 |
Interactions and Pathways
Plasmids
No data available