Gene
meis2b
- ID
- ZDB-GENE-000210-23
- Name
- Meis homeobox 2b
- Symbol
- meis2b Nomenclature History
- Previous Names
-
- meis2.1
- meis2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity. Involved in cardiac atrium morphogenesis and heart looping. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; heart rudiment; nervous system; neural plate; and pericardial region. Human ortholog(s) of this gene implicated in cleft palate, cardiac defects, and intellectual disabillity. Orthologous to human MEIS2 (Meis homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76815 (20 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Cleft palate, cardiac defects, and impaired intellectual development | 600987 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR032453 | Homeobox protein PKNOX/Meis, N-terminal |
Domain Details Per Protein
Protein | Length | Homeobox protein PKNOX/Meis, N-terminal |
---|---|---|
UniProtKB:Q9DDE0
|
||
UniProtKB:Q9PTM7
|
393 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
meis2b-203
(1)
|
Havana | 3104 nt | |
ncRNA |
meis2b-002
(1)
|
Havana | 843 nt |
Interactions and Pathways
No data available
Plasmids
No data available