ZFIN ID: ZDB-GENE-000210-21
Gene Name: inhibin subunit beta Aa
Gene Symbol: inhbaa    Nomenclature History

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Previous Names: actba, inhba, activin beta A1 (1), activin beta A, fk40h12, wu:fk40h12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have cytokine activity. Involved in cardiac muscle myoblast proliferation and fin regeneration. Predicted to localize to extracellular space. Is expressed in several structures, including anterior axial hypoblast; gonad; hatching gland; polster; and trigeminal ganglion. Orthologous to human INHBA (inhibin subunit beta A).
Genome Resources: Alliance (1),  Gene:30072 (1),  Ensembl(GRCz11):ENSDARG00000012671 (2)
GENE EXPRESSION
All Expression Data: 21 figures from 10 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [IMAGE:7159391]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns37 Small Deletion Unknown Unknown TALEN
hu2843 Point Mutation Unknown Unknown ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-inhbaa N/A 1
TALEN-inhbaa 1
PHENOTYPE
Data: text only from Jazwinska et al., 2007
Observed in:
DISEASE ASSOCIATED WITH inhbaa HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH inhbaa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process fin regeneration (more)
Cellular Component extracellular region (more)
Molecular Function growth factor activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA inhbaa-201 (1)    Ensembl 3593
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM inhbaa
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(myl7:inhbaa-2A-Hsa.HISTH2BJ-EGFP) myl7 2AEGFPinhbaa Danio rerioHomo sapiens 1 2
MARKER RELATIONSHIPS
inhbaa Contained in: [BAC] DKEY-232F4 (1) (order this)
inhbaa Encodes: [EST] fk40h12, IMAGE:7159391 (1)
[cDNA] MGC:65729 (1), MGC:76801 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_130916 (1) 3424 nt
Genomic GenBank:CR931801 (1) 142470 nt
Select Tool
Polypeptide UniProtKB:Q8QGE3 (1) 395 aa
Sequence Information (all 20)
ORTHOLOGY for inhbaa ( Chr: 24 )
CITATIONS (55)