Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-000208-18
Gene Name: uroporphyrinogen decarboxylase
Gene Symbol: urod
Previous Names: wu:fc43e09 (1), yqe, yquem (1)
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (5 images) from Rauch et al., 2003 [fc43e09]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  blood, intermediate cell mass of mesoderm, presumptive blood, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 genotypes
Alleles: sa19778, tp61
Knockdown reagents: MO1-urod (1), MO2-urod (1)
PHENOTYPE
Data: 3 figures from 3 publications
Observed in: anatomical system, blood, heart, nucleate erythrocyte (all 7) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Porphyria cutanea tarda 176100
Porphyria, hepatoerythropoietic 176100
GENE ONTOLOGY
Ontology GO Term
Biological Process porphyrin-containing compound metabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function uroporphyrinogen decarboxylase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000257 (1)
  • InterPro:IPR006361 (1)
  • PROSITE:PS00906 (1)
  • PROSITE:PS00907 (1)
  • Pfam:PF01208 (1)
  • EC:4.1.1.37 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA urod-001 (1) 1292
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM urod
    Tg(gata1a:urod-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    urod Contained in: [BAC] CH73-38P6 (1) (order this)
    urod Contains: [STS] unp1690
    urod Encodes: [EST] fc43e09 (1)
    [cDNA] MGC:123153 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131347 (1) 1414 bp
    Genomic GenBank:CU571330 (1) 133116 bp
    Select Tool
    Polypeptide UniProtKB:Q568V5 (1) 402 aa
    Sequence Clusters UniGene:2166 (1)
    Sequence Information (all 17)
    OTHER urod GENE PAGES
  • Gene:30617 (1)
  • VEGA:OTTDARG00000029046 (1)
  • Ensembl(Zv9):ENSDARG00000006818 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish urod 2  
    Human UROD 1 (1p34)
  • OMIM:613521
  • Gene:7389
  • Mouse Urod 4 ( 53.41 cM)
  • MGI:98916
  • Gene:22275
  • Orthology Details
    CITATIONS (35)