Gene

urod

ID
ZDB-GENE-000208-18
Name
uroporphyrinogen decarboxylase
Symbol
urod Nomenclature History
Previous Names
  • wu:fc43e09 (1)
  • yqe
  • yquem (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits uroporphyrinogen decarboxylase activity. Involved in porphyrin-containing compound metabolic process. Predicted to localize to cytosol. Is expressed in blood; intermediate cell mass of mesoderm; and presumptive blood. Used to study hepatoerythropoietic porphyria. Human ortholog(s) of this gene implicated in porphyria cutanea tarda. Orthologous to human UROD (uroporphyrinogen decarboxylase).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With urod Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
porphyria cutanea tarda Alliance Porphyria cutanea tarda 176100
porphyria cutanea tarda Alliance Porphyria, hepatoerythropoietic 176100
Associated With urod Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000257 Uroporphyrinogen decarboxylase (URO-D)
Family IPR006361 Uroporphyrinogen decarboxylase HemE
Homologous_superfamily IPR038071 UROD/MetE-like superfamily
Domain Details Per Protein
Protein Length UROD/MetE-like superfamily Uroporphyrinogen decarboxylase HemE Uroporphyrinogen decarboxylase (URO-D)
UniProtKB:Q9PTS2 369
UniProtKB:Q32PL0 369
UniProtKB:Q568V5 402
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations