ZFIN ID: ZDB-GENE-000208-18
Gene Name: uroporphyrinogen decarboxylase
Gene Symbol: urod
Previous Names: wu:fc43e09 (1), yqe, yquem (1)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 10 figures from 4 publications
Directly Submitted Expression Data: 6 figures (5 images) from Rauch et al., 2003 [fc43e09]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  blood, intermediate cell mass of mesoderm, presumptive blood, unspecified
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa19778 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tp61 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-urod (1), CRISPR2-urod (1), MO1-urod (1), MO2-urod (1)
    PHENOTYPE
    Data: 4 figures from 4 publications
    Observed in: anatomical system, blood, heart, nucleate erythrocyte (all 7) expand
    DISEASE ASSOCIATED WITH urod HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    porphyria cutanea tarda Porphyria cutanea tarda 176100
    Porphyria, hepatoerythropoietic 176100
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process porphyrin-containing compound metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function uroporphyrinogen decarboxylase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000257 (1)
  • InterPro:IPR006361 (1)
  • PROSITE:PS00906 (1)
  • PROSITE:PS00907 (1)
  • Pfam:PF01208 (1)
  • EC:4.1.1.37 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA urod-001 (1) 1292
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM urod
    Tg(gata1a:urod-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    urodContained in: [BAC] CH73-38P6 (1) (order this)
    urodContains: [STS] unp1690
    urodEncodes: [EST] fc43e09 (1) (order this)
    [cDNA] MGC:123153 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131347 (1) 1414bp
    Genomic GenBank:CU571330 (1) 133116bp
    Select Tool
    Polypeptide UniProtKB:Q568V5 (1) 402aa
    Sequence Clusters UniGene:2166 (1)
    Sequence Information (all 17)
    OTHER urod GENE PAGES
  • Gene:30617 (1)
  • VEGA:OTTDARG00000029046 (1)
  • Ensembl(GRCz10):ENSDARG00000006818 (1)
  • ORTHOLOGY for urod (Chr: 2)
    Species Symbol Chromosome Accession # Evidence
    Human UROD 1
  • Gene:7389
  • OMIM:613521
  • HGNC:12591
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Urod 4
  • MGI:98916
  • Gene:22275
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (39)