ZFIN ID: ZDB-GENE-000208-18
Gene Name: uroporphyrinogen decarboxylase
Gene Symbol: urod
Previous Names: wu:fc43e09 (1), yqe, yquem (1)
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (5 images) from Rauch et al., 2003 [fc43e09]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  blood, intermediate cell mass of mesoderm, presumptive blood, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 Genotypes
Knockdown reagents: CRISPR1-urod (1), CRISPR2-urod (1), MO1-urod (1), MO2-urod (1)

Allele Type Mutagen Suppliers
sa19778 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp61 Point Mutation ENU
  • Nüsslein-Volhard Lab
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in: anatomical system, blood, heart, nucleate erythrocyte (all 7) expand
    DISEASE ASSOCIATED WITH urod HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    porphyria cutanea tarda Porphyria cutanea tarda 176100
    Porphyria, hepatoerythropoietic 176100
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process porphyrin-containing compound metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function uroporphyrinogen decarboxylase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000257 (1)
  • InterPro:IPR006361 (1)
  • PROSITE:PS00906 (1)
  • PROSITE:PS00907 (1)
  • Pfam:PF01208 (1)
  • EC:4.1.1.37 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA urod-001 (1) 1292
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM urod
    Tg(gata1a:urod-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    urod Contained in: [BAC] CH73-38P6 (1) (order this)
    urod Contains: [STS] unp1690
    urod Encodes: [EST] fc43e09 (1) (order this)
    [cDNA] MGC:123153 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131347 (1) 1414 bp
    Genomic GenBank:CU571330 (1) 133116 bp
    Select Tool
    Polypeptide UniProtKB:Q568V5 (1) 402 aa
    Sequence Clusters UniGene:2166 (1)
    Sequence Information (all 17)
    OTHER urod GENE PAGES
  • Gene:30617 (1)
  • VEGA:OTTDARG00000029046 (1)
  • Ensembl(Zv9):ENSDARG00000006818 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish urod 2  
    Human UROD 1 (1p34)
  • OMIM:613521
  • Gene:7389
  • Mouse Urod 4 ( 53.41 cM)
  • MGI:98916
  • Gene:22275
  • Orthology Details
    CITATIONS (38)