ZFIN ID: ZDB-FISH-200723-7
Fish name: cacna2d4azh5/zh5; cacna2d4bzh6/zh6(TU)
Genotype: cacna2d4azh5/zh5; cacna2d4bzh6/zh6 (TU)
Targeting Reagent: none
HUMAN DISEASE MODELED by cacna2d4azh5/zh5; cacna2d4bzh6/zh6(TU)
Human Disease Conditions Citations
cone dystrophy standard conditions Schlegel et al., 2019
GENE EXPRESSION
Gene expression in cacna2d4azh5/zh5; cacna2d4bzh6/zh6(TU)
Reporter gene expression No data available
PHENOTYPE
Phenotype in cacna2d4azh5/zh5; cacna2d4bzh6/zh6(TU)
Phenotype Conditions Figures
eye decreased size, abnormal standard conditions Fig. 5 with image from Schlegel et al., 2019
eye photoreceptor cell synaptic ribbon separated from eye photoreceptor cell photoreceptor ribbon synapse, abnormal standard conditions Fig. 7 with image from Schlegel et al., 2019
retina layer formation normal process quality, normal standard conditions Fig. 5 with image from Schlegel et al., 2019
retinal cone cell chemical synaptic transmission decreased process quality, abnormal standard conditions Fig. 3 with imageFig. 4 with image from Schlegel et al., 2019
retinal cone cell development decreased process quality, abnormal standard conditions Fig. 3 with imageFig. 4 with imageFig. 7 with image from Schlegel et al., 2019
retinal outer nuclear layer morphology, normal standard conditions Fig. 5 with image from Schlegel et al., 2019
retinal outer plexiform layer cacna1fa expression decreased amount, abnormal standard conditions Fig. 2 with image from Schlegel et al., 2019
retinal outer plexiform layer has fewer parts of type eye photoreceptor cell synaptic ribbon, abnormal standard conditions Fig. 7 with image from Schlegel et al., 2019
retinal outer plexiform layer has normal numbers of parts of type eye photoreceptor cell photoreceptor ribbon synapse, normal standard conditions Fig. 7 with image from Schlegel et al., 2019
retinal outer plexiform layer morphology, normal standard conditions Fig. 5 with image from Schlegel et al., 2019
retinal photoreceptor layer ctbp2l expression mislocalised, abnormal standard conditions Fig. 6 with image from Schlegel et al., 2019
retinal photoreceptor layer cacna1fa expression mislocalised, abnormal standard conditions Fig. 2 with image from Schlegel et al., 2019

CITATIONS  (1)