ZFIN ID: ZDB-FISH-190205-11
Fish name: npc1ihb334/ihb334
Genotype: npc1ihb334/ihb334
Targeting Reagent: none
HUMAN DISEASE MODELED by npc1ihb334/ihb334
Human Disease Conditions Citations
Niemann-Pick disease type C1 standard conditions Lin et al., 2018
GENE EXPRESSION
Gene expression in npc1ihb334/ihb334
RNA expression No data available
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in npc1ihb334/ihb334
Phenotype Conditions Figures
cerebellum Purkinje cell decreased amount, abnormal standard conditions Fig. 3 from Lin et al., 2018
hepatocyte morphology, abnormal standard conditions Fig. 3 from Lin et al., 2018
hepatocyte vacuolated, abnormal standard conditions Fig. 3 from Lin et al., 2018
liver fatty, abnormal standard conditions Fig. 3 from Lin et al., 2018
liver cholesterol increased amount, abnormal standard conditions Fig. 3 from Lin et al., 2018
liver sphingolipid increased amount, abnormal standard conditions Fig. 4 from Lin et al., 2018
locomotory behavior process quality, abnormal standard conditions Fig. S Movie 1 from Lin et al., 2018
whole organism dead, abnormal standard conditions Fig. 2 from Lin et al., 2018
whole organism decreased length, abnormal standard conditions Fig. 2 from Lin et al., 2018
whole organism decreased life span, abnormal standard conditions Fig. 2 from Lin et al., 2018

CITATIONS  (1)