ZFIN Fish: WT + MO1-znfl1

ZFIN ID: ZDB-FISH-180627-4

ZFIN ID: ZDB-FISH-180627-4

Fish name:	WT + MO1-znfl1
Genotype:	WT
Targeting Reagent:	MO1-znfl1

HUMAN DISEASE MODELED by WT + MO1-znfl1
No data available

GENE EXPRESSION
Gene expression in WT + MO1-znfl1

RNA expression

Expressed Gene	Structure	Conditions	Figures
cyp26a1	mesoderm neuroectoderm	standard conditions	Fig. 2 from Li et al., 2018
egr2b	rhombomere rhombomere 3 rhombomere 5 whole organism	standard conditions	Fig. 1 , Fig. 2 , Fig. 3 from Li et al., 2018 Fig. 4 from Dong et al., 2017
	neuroectoderm rhombomere 3 rhombomere 5	chemical treatment by environment: all-trans-retinoic acid	Fig. 3 from Li et al., 2018
en2a	midbrain hindbrain boundary midbrain hindbrain boundary neural rod rhombomere	standard conditions	Fig. 1 , Fig. 2 from Li et al., 2018 Fig. 4 from Dong et al., 2017
hoxb1a	notochord presumptive rhombomere 4	standard conditions	Fig. 3 from Dong et al., 2017
hoxb1b	neuroectoderm notochord presumptive rhombomere 4	standard conditions	Fig. 3 from Dong et al., 2017
hoxb4a	hindbrain	standard conditions	Fig. 2 from Li et al., 2018
hoxd4a	hindbrain neural plate presumptive rhombomere 7 presumptive rhombomere 8 rhombomere	standard conditions	Fig. 3, Fig. 4 from Dong et al., 2017
mafba	rhombomere 5 rhombomere 6	standard conditions	Fig. 1 from Li et al., 2018
myod1	somite	standard conditions	Fig. 1 , Fig. 3 from Li et al., 2018
	somite	chemical treatment by environment: all-trans-retinoic acid	Fig. 3 from Li et al., 2018
otx2b	neuroectoderm	standard conditions	Fig. 3 from Dong et al., 2017
pou5f3	whole organism	standard conditions	Fig. 5, Fig. 6, Fig. 7 from Dong et al., 2017
sall4	whole organism	standard conditions	Fig. 6 from Dong et al., 2017

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO1-znfl1

Phenotype	Conditions	Figures
forebrain decreased length, abnormal	standard conditions	Fig. 4 from Dong et al., 2017
hindbrain hoxb4a expression decreased amount, abnormal	standard conditions	Fig. 2 from Li et al., 2018
hindbrain decreased length, abnormal	standard conditions	Fig. 4 from Dong et al., 2017
hindbrain neural plate hoxd4a expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
mesoderm cyp26a1 expression decreased amount, abnormal	standard conditions	Fig. 2 from Li et al., 2018
neuroectoderm hoxb1b expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
neuroectoderm cyp26a1 expression decreased amount, abnormal	standard conditions	Fig. 2 from Li et al., 2018
neuroectoderm otx2b expression increased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
neuroectoderm otx2b expression increased distribution, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
notochord hoxb1b expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
notochord hoxb1a expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
presumptive rhombomere 4 hoxb1a expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
presumptive rhombomere 4 hoxb1b expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
presumptive rhombomere 7 hoxd4a expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
presumptive rhombomere 8 hoxd4a expression decreased amount, abnormal	standard conditions	Fig. 3 from Dong et al., 2017
rhombomere 6 decreased distance somite 1, abnormal	standard conditions	Fig. 1 , Fig. 3 from Li et al., 2018
rhombomere 6 distance somite 1, ameliorated	chemical treatment by environment: all-trans-retinoic acid	Fig. 3 from Li et al., 2018
rhombomere 7 decreased distance somite 1, abnormal	standard conditions	Fig. 1 from Li et al., 2018
whole organism sall4 expression decreased amount, abnormal	standard conditions	Fig. 6 from Dong et al., 2017
whole organism pou5f3 expression decreased amount, abnormal	standard conditions	Fig. 5, Fig. 6, Fig. 7 from Dong et al., 2017

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