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General Information
ZIRC
ZFIN ID: ZDB-FISH-180410-6
Fish name: mettl3ihb307/ihb307(AB)
Genotype: mettl3ihb307/ihb307 (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by mettl3ihb307/ihb307(AB)
Human Disease Conditions Citations
infertility standard conditions Xia et al., 2017
GENE EXPRESSION
Gene expression in mettl3ihb307/ihb307(AB)
RNA expression
Expressed Gene Structure Conditions Figures
acvr2aa standard conditions Fig. 9 from Xia et al., 2017
acvr2ba standard conditions Fig. 9 from Xia et al., 2017
amh standard conditions Fig. 9 from Xia et al., 2017
cyp11a1 standard conditions Fig. 9 from Xia et al., 2017
cyp17a1 standard conditions Fig. 9 from Xia et al., 2017
cyp17a2 standard conditions Fig. 9 from Xia et al., 2017
cyp19a1a standard conditions Fig. 9 from Xia et al., 2017
cyp19a1b standard conditions Fig. 9 from Xia et al., 2017
cyp26b1 standard conditions Fig. 9 from Xia et al., 2017
esr1 standard conditions Fig. 9 from Xia et al., 2017
esr2a standard conditions Fig. 9 from Xia et al., 2017
esr2b standard conditions Fig. 9 from Xia et al., 2017
fshb standard conditions Fig. 9 from Xia et al., 2017
fshr standard conditions Fig. 9 from Xia et al., 2017
fsta standard conditions Fig. 9 from Xia et al., 2017
gh1 standard conditions Fig. 9 from Xia et al., 2017
hsd3b2 standard conditions Fig. 9 from Xia et al., 2017
hsd17b3 standard conditions Fig. 9 from Xia et al., 2017
igf3 standard conditions Fig. 9 from Xia et al., 2017
lhb standard conditions Fig. 9 from Xia et al., 2017
lhcgr standard conditions Fig. 9 from Xia et al., 2017
pgr standard conditions Fig. 9 from Xia et al., 2017
piwil1 standard conditions Fig. 9 from Xia et al., 2017
prl standard conditions Fig. 9 from Xia et al., 2017
ptgs2a standard conditions Fig. 9 from Xia et al., 2017
ptgs2b standard conditions Fig. 9 from Xia et al., 2017
star standard conditions Fig. 9 from Xia et al., 2017
sycp1 standard conditions Fig. 7 from Xia et al., 2017
sycp3 standard conditions Fig. 7 from Xia et al., 2017
wt1a standard conditions Fig. 9 from Xia et al., 2017
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in mettl3ihb307/ihb307(AB)
Phenotype Conditions Figures
blood 11-oxotestosterone decreased amount, abnormal standard conditions Fig. 10 from Xia et al., 2017
blood estradiol decreased amount, abnormal standard conditions Fig. 10 from Xia et al., 2017
brain mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity decreased occurrence, abnormal standard conditions Fig. 3 from Xia et al., 2017
female organism decreased female fertility, abnormal standard conditions Fig. 8 from Xia et al., 2017
female organism has fewer parts of type oocyte stage V, abnormal standard conditions Fig. 8 from Xia et al., 2017
female organism proportionality to male organism, abnormal standard conditions Fig. 8 from Xia et al., 2017
female organism hypophysis lhb expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
female organism ovulation decreased rate, abnormal standard conditions Fig. 8 from Xia et al., 2017
flagellated sperm motility decreased process quality, abnormal standard conditions text only from Xia et al., 2017
liver mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity decreased occurrence, abnormal standard conditions Fig. 3 from Xia et al., 2017
male organism hypophysis fshb expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
muscle mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity decreased occurrence, abnormal standard conditions Fig. 3 from Xia et al., 2017
oocyte stage IV meiosis II nuclear envelope disassembly disrupted, abnormal standard conditions Fig. 5 from Xia et al., 2017
oocyte stage IV meiosis II nuclear envelope disassembly disrupted, ameliorated chemical treatment by injection: (20R)-17,20-dihydroxypregn-4-en-3-one Fig. 5 from Xia et al., 2017
oocyte stage IV meiosis II nuclear envelope disassembly disrupted, ameliorated chemical treatment: Chorionic gonadotropin Fig. 5 from Xia et al., 2017
oocyte stage IV oocyte maturation disrupted, abnormal standard conditions Fig. 5 from Xia et al., 2017
ovarian follicle stage IV pgr expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovarian follicle stage IV star expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovarian follicle stage IV hsd3b2 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovarian follicle stage IV igf3 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovarian follicle stage IV cyp19a1a expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovarian follicle stage IV fsta expression increased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
ovary decreased size, abnormal standard conditions Fig. 4 from Xia et al., 2017
ovary has fewer parts of type ovarian follicle stage IV, abnormal standard conditions Fig. 4 from Xia et al., 2017
ovary mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity decreased occurrence, abnormal standard conditions Fig. 3 from Xia et al., 2017
sex determination process quality, abnormal standard conditions Fig. 8 from Xia et al., 2017
testis cyp17a1 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis hsd17b3 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis hsd3b2 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis fshr expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis cyp11a1 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis star expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis cyp17a2 expression decreased amount, abnormal standard conditions Fig. 9 from Xia et al., 2017
testis decreased size, abnormal standard conditions Fig. 6 from Xia et al., 2017
testis has extra parts of type spermatocyte, abnormal standard conditions Fig. 6 from Xia et al., 2017
testis has extra parts of type spermatogonium, abnormal standard conditions Fig. 6 from Xia et al., 2017
testis lacks parts or has fewer parts of type sperm, abnormal standard conditions Fig. 6 from Xia et al., 2017
testis mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity decreased occurrence, abnormal standard conditions Fig. 3 from Xia et al., 2017
whole organism brood viability, abnormal standard conditions text only from Xia et al., 2017

CITATIONS  (1)