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General Information
ZIRC
ZFIN ID: ZDB-FISH-170620-12
Fish name: ubs3Tg ; cdh5ubs8/ubs8 ; s916Tg ; esamaubs19/ubs19 ; ubs18Tg
Genotype: ubs3Tg ; cdh5ubs8/ubs8 ; s916Tg ; esamaubs19/ubs19 ; ubs18Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by ubs3Tg ; cdh5ubs8/ubs8 ; s916Tg ; esamaubs19/ubs19 ; ubs18Tg
No data available
GENE EXPRESSION
Gene expression in ubs3Tg ; cdh5ubs8/ubs8 ; s916Tg ; esamaubs19/ubs19 ; ubs18Tg
RNA expression No data available
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in ubs3Tg ; cdh5ubs8/ubs8 ; s916Tg ; esamaubs19/ubs19 ; ubs18Tg
Phenotype Conditions Figures
actin cytoskeleton organization disrupted, abnormal standard conditions Fig. 4 with image from Sauteur et al., 2017
actin filament reorganization disrupted, abnormal standard conditions Fig. 4 with image from Sauteur et al., 2017
angiogenic sprout has extra parts of type endothelial cell filopodium, abnormal standard conditions Fig. 3 with image from Sauteur et al., 2017
angiogenic sprout endothelial tip cell detached from angiogenic sprout, exacerbated standard conditions Fig. 3 with image from Sauteur et al., 2017
apical junction assembly disrupted, abnormal standard conditions Fig. 4 with image from Sauteur et al., 2017
cell adhesion involved in sprouting angiogenesis disrupted, abnormal standard conditions Fig. 4 with image from Sauteur et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development delayed, abnormal standard conditions Fig. 3 with image from Sauteur et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development delayed, exacerbated standard conditions Fig. 4 with image from Sauteur et al., 2017
endothelial tip cell aggregated, abnormal standard conditions Fig. 3 with image from Sauteur et al., 2017
endothelial tip cell actin filament bundle of filopodium decreased amount, abnormal standard conditions Fig. 3 with imageFig. 4 with image from Sauteur et al., 2017
endothelial tip cell cell adhesion decreased efficacy, exacerbated standard conditions Fig. 3 with imageFig. 4 with image from Sauteur et al., 2017

CITATIONS  (1)