ZFIN ID: ZDB-FISH-150901-29665
Fish name: krit1ty219c/ty219c
Genotype: krit1ty219c/ty219c
Targeting Reagent: none
HUMAN DISEASE MODELED by krit1ty219c/ty219c
Human Disease Conditions Citations
cerebral cavernous malformation 1 control Rödel et al., 2019
GENE EXPRESSION
Gene expression in krit1ty219c/ty219c
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab1-cdh5 control Fig. 1 from Rödel et al., 2019
Reporter gene expression No data available
PHENOTYPE
Phenotype in krit1ty219c/ty219c
Phenotype Conditions Figures
anatomical system quality, abnormal standard conditions Fig. for (ty219c) with image from Phenotype Annotation (1994-2006)
atrial endocardium notch1b expression mislocalised, abnormal standard conditions Fig. 4 with image from Donat et al., 2018
atrial endocardium klf2a expression mislocalised, abnormal standard conditions Fig. 3 with image from Donat et al., 2018
atrioventricular valve morphogenesis decreased process quality, abnormal standard conditions Fig. 4 with image from Donat et al., 2018
atrium increased size, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
blood circulation disrupted, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
bulbus arteriosus increased size, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
cardiac ventricle increased size, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
endocardium klf2a expression increased amount, abnormal standard conditions Fig. 3 with image from Donat et al., 2018
endocardium klf2a expression increased distribution, abnormal standard conditions Fig. 3 with image from Donat et al., 2018
heart quality, abnormal standard conditions Fig. for (ty219c) with image from Phenotype Annotation (1994-2006)
heart morphogenesis disrupted, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
lateral dorsal aorta endothelial cell elongated, abnormal control Fig. 1 from Rödel et al., 2019
lateral dorsal aorta endothelial cell increased area, abnormal control Fig. 1 from Rödel et al., 2019
myocardium decreased distance endocardium, abnormal standard conditions Fig. 4 with image from Chen et al., 1996
ventricular endocardium notch1b expression mislocalised, abnormal standard conditions Fig. 4 with image from Donat et al., 2018
ventricular endocardium klf2a expression mislocalised, abnormal standard conditions Fig. 3 with image from Donat et al., 2018
ventricular endocardium Notch signaling involved in heart development increased occurrence, abnormal standard conditions Fig. 4 with image from Donat et al., 2018
whole organism lethal (sensu genetics), abnormal standard conditions Fig. for (ty219c) with image from Phenotype Annotation (1994-2006)

CITATIONS  (9)