ZFIN ID: ZDB-FISH-150901-29460
Fish name: tsc2vu242/vu242 (AB)
Genotype: tsc2vu242/vu242 (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by tsc2vu242/vu242 (AB)
Human Disease Conditions Citations
tuberous sclerosis standard conditions Kim et al., 2011
GENE EXPRESSION
Gene expression in tsc2vu242/vu242 (AB)
RNA expression
Expressed Gene Structure Conditions Figures
eif4ebp1 standard conditions Fig. 2 with image from Kim et al., 2011
Reporter gene expression No data available
PHENOTYPE
Phenotype in tsc2vu242/vu242 (AB)
Phenotype Conditions Figures
brain morphology, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
brain protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
CNS neuron (sensu Vertebrata) mislocalised, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
diencephalon anterior region disorganized, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
dorsal telencephalon disorganized, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
dorsal telencephalon increased size, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
eye protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
intestine protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
kidney protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
liver increased size, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
liver protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
negative regulation of TOR signaling disrupted, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
neuron migration disrupted, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
spinal cord protein serine/threonine kinase activity increased occurrence, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
swim bladder collapsed, abnormal standard conditions Fig. 2 with image from Kim et al., 2011
telencephalic ventricle morphology, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
telencephalic white matter composition, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
ventral telencephalon dorsal region disorganized, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
ventral telencephalon dorsal region increased width, abnormal standard conditions Fig. 5 with image from Kim et al., 2011
whole organism viability, abnormal standard conditions text only from Kim et al., 2011

CITATIONS  (3)