ZFIN ID: ZDB-FISH-150901-17579
Fish name: ift88tz288/tz288
Genotype: ift88tz288/tz288
Targeting Reagent: none

HUMAN DISEASE MODELED by ift88tz288/tz288
No data available
GENE EXPRESSION
Gene expression in ift88tz288/tz288
Expressed Gene Structure Conditions Figures
adgrv1 hair cell standard conditions Fig. 7 with image from Blanco et al., 2014
evx1 cloaca, cloacal chamber standard conditions Fig. 4 from Slanchev et al., 2011
gata3 posterior pronephric duct standard conditions Fig. 4 from Slanchev et al., 2011
gli1 central nervous system, somite posterior-most region standard conditions Fig. 3 with image from Lunt et al., 2009
gli3 central nervous system standard conditions Fig. 3 with image from Lunt et al., 2009
ift52 whole organism standard conditions Fig. 6 with imageFig. 8 with image from Sukumaran et al., 2009
ift88 (not) hair cell, (not) whole organism standard conditions Fig. 2 with image from Blanco et al., 2014
Fig. 6 with imageFig. 8 with image from Sukumaran et al., 2009
nkx2.2a hindbrain, midbrain ventral region standard conditions Fig. 3 with image from Lunt et al., 2009
opn1sw2 blue sensitive photoreceptor cell standard conditions Fig. 2 from Krock et al., 2008
pax6a eye, neural tube standard conditions Fig. 4 with image from Lunt et al., 2009
pitx3 adenohypophyseal placode standard conditions Fig. 4 with image from Lunt et al., 2009
prdm1a cloaca, cloacal chamber standard conditions Fig. 4 from Slanchev et al., 2011
ptch1 neural tube standard conditions Fig. 3 with image from Lunt et al., 2009
ptch2 diencephalon, floor plate, neural tube (all 6) expand standard conditions Fig. 3 with imageFig. 5 with image from Lunt et al., 2009
neural tube, somite chemical treatment: Cyclopamine Fig. 8 with image from Lunt et al., 2009
rho retinal rod cell standard conditions Fig. 1 with image from Nakao et al., 2012
Fig. 2Fig. 3 from Krock et al., 2008
shha diencephalon, floor plate, notochord (all 4) expand standard conditions Fig. 5 with image from Lunt et al., 2009
tbx2b posterior pronephric duct standard conditions Fig. 4 from Slanchev et al., 2011
ush1c (not) hair cell standard conditions Fig. 2 with image from Blanco et al., 2014
whrnb hair cell standard conditions Fig. 7 with image from Blanco et al., 2014
PHENOTYPE 
Phenotype in ift88tz288/tz288
Phenotype Conditions Figures
anterior macula stereocilium bundle bent, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
anterior macula stereocilium bundle splayed, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
blue sensitive photoreceptor cell morphology, abnormal standard conditions Fig. 2 from Krock et al., 2008
cell differentiation occurrence, normal standard conditions Fig. 1 from Krock et al., 2008
cilium assembly decreased process quality, abnormal chemical treatment: prostaglandin E2 Fig. 8 from Jin et al., 2014
cilium assembly decreased process quality, abnormal control Fig. 8 from Jin et al., 2014
cilium assembly disrupted, abnormal standard conditions Fig. 2 with image from Lunt et al., 2009
Fig. 1 from Omori et al., 2008
eye decreased size, abnormal standard conditions Fig. S1 from Krock et al., 2008
eye photoreceptor cell apoptotic, abnormal control Fig. S3 with image from Bachmann-Gagescu et al., 2015
eye photoreceptor cell cilium absent, abnormal standard conditions Fig. 2 from Krock et al., 2008
eye photoreceptor cell nucleus decreased length, abnormal standard conditions Fig. 3 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor connecting cilium absent, abnormal standard conditions Fig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor inner segment membrane disorganized, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor inner segment membrane displaced, abnormal standard conditions Fig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor outer segment absent, abnormal standard conditions Fig. 1 with imageFig. 2 with imageFig. 3 with image from Sukumaran et al., 2009
hair cell anterior macula normal amount, normal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula apoptotic process increased occurrence, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula cilium decreased length, abnormal control Fig. 8 from Jin et al., 2014
hair cell anterior macula cilium decreased length, abnormal chemical treatment: prostaglandin E2 Fig. 8 from Jin et al., 2014
hair cell anterior macula epithelium organization quality, normal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula stereocilium decreased amount, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
intraciliary transport disrupted, abnormal standard conditions Fig. 3 from Krock et al., 2008
neural tube axoneme absent, abnormal standard conditions Fig. 2 with image from Lunt et al., 2009
neurocranium morphology, normal standard conditions Fig. 7 with image from Lunt et al., 2009
photoreceptor cell decreased amount, abnormal constant light Fig. 1 with image from Nakao et al., 2012
photoreceptor cell ciliary basal body mislocalised, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
post-vent region curved ventral, abnormal standard conditions Fig. S1 from Krock et al., 2008
pronephros cystic, abnormal standard conditions Fig. S1 from Krock et al., 2008
retina photoreceptor outer segment absent, abnormal standard conditions Fig. 1Fig. 3Fig. 4 from Krock et al., 2008
retinal cone cell absence due to degeneration, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal cone cell decreased amount, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal cone cell decreased length, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal cone cell morphology, abnormal standard conditions Fig. 5 with imageFig. 7 with imageFig. 9 with image from Sukumaran et al., 2009
retinal outer nuclear layer perforate, abnormal standard conditions Fig. 1 from Krock et al., 2008
retinal outer nuclear layer eye photoreceptor cell apoptotic, abnormal standard conditions Fig. 1 from Krock et al., 2008
retinal photoreceptor layer apoptotic process increased occurrence, abnormal control Fig. S3 with image from Bachmann-Gagescu et al., 2015
retinal photoreceptor layer eye photoreceptor cell apoptotic, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal rod cell absence due to degeneration, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal rod cell decreased amount, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal rod cell morphology, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal rod cell pigmented, abnormal standard conditions Fig. 1 with image from Nakao et al., 2012
somite cellular quality, normal standard conditions Fig. 9 with image from Lunt et al., 2009
somite shape, normal standard conditions Fig. 9 with image from Lunt et al., 2009
whole organism curved ventral, abnormal standard conditions Fig. S8 with image from Coxam et al., 2014

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