ZFIN ID: ZDB-FISH-150901-17579
Fish name: ift88tz288/tz288
Genotype: ift88tz288/tz288
Targeting Reagent: none
HUMAN DISEASE MODELED by ift88tz288/tz288
No data available
GENE EXPRESSION
Gene expression in ift88tz288/tz288
RNA expression
Expressed Gene Structure Conditions Figures
adgrv1 standard conditions Fig. 7 with image from Blanco et al., 2014
evx1 standard conditions Fig. 4 from Slanchev et al., 2011
gata3 standard conditions Fig. 4 from Slanchev et al., 2011
gli1 standard conditions Fig. 3 with image from Lunt et al., 2009
gli3 standard conditions Fig. 3 with image from Lunt et al., 2009
ift52 standard conditions Fig. 6 with imageFig. 8 with image from Sukumaran et al., 2009
ift88 standard conditions Fig. 2 with image from Blanco et al., 2014
Fig. 6 with imageFig. 8 with image from Sukumaran et al., 2009
nkx2.2a standard conditions Fig. 3 with image from Lunt et al., 2009
opn1sw2 standard conditions Fig. 2 from Krock et al., 2008
pax6a standard conditions Fig. 4 with image from Lunt et al., 2009
pitx3 standard conditions Fig. 4 with image from Lunt et al., 2009
prdm1a standard conditions Fig. 4 from Slanchev et al., 2011
ptch1 standard conditions Fig. 3 with image from Lunt et al., 2009
ptch2 standard conditions Fig. 3 with imageFig. 5 with image from Lunt et al., 2009
chemical treatment: Cyclopamine Fig. 8 with image from Lunt et al., 2009
rho standard conditions Fig. 1 with image from Nakao et al., 2012
Fig. 2Fig. 3 from Krock et al., 2008
shha standard conditions Fig. 5 with image from Lunt et al., 2009
tbx2b standard conditions Fig. 4 from Slanchev et al., 2011
ush1c standard conditions Fig. 2 with image from Blanco et al., 2014
whrnb standard conditions Fig. 7 with image from Blanco et al., 2014
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab2-myo7a standard conditions Fig. 2 with image from Blanco et al., 2014
Ab-S58 standard conditions Fig. 9 with image from Lunt et al., 2009
zpr-1 standard conditions Fig. 2 from Feng et al., 2017
Fig. 3 from Pooranachandran et al., 2016
Fig. 5 with imageFig. 7 with imageFig. 9 with image from Sukumaran et al., 2009
Ab1-opn1sw2 standard conditions Fig. 5 with imageFig. 7 with imageFig. 9 with image from Sukumaran et al., 2009
Ab1-ush2a standard conditions Fig. 7 with image from Blanco et al., 2014
Ab1-tuba chemical treatment: prostaglandin E2 Fig. 8 from Jin et al., 2014
Ab1-rho standard conditions Fig. 5 with imageFig. 7 with imageFig. 9 with image from Sukumaran et al., 2009
Ab1-ift52 standard conditions Fig. 5 with imageFig. 6 with imageFig. 7 with imageFig. 8 with imageFig. 9 with image from Sukumaran et al., 2009
Ab1-cdh23 standard conditions Fig. 2 with image from Blanco et al., 2014
Ab1-tubg1 standard conditions Fig. 2 with image from Lunt et al., 2009
Ab2-isl standard conditions Fig. 9 with image from Lunt et al., 2009
Ab1-tuba standard conditions Fig. 8 from Jin et al., 2014
Fig. 2 with image from Lunt et al., 2009
Ab1-ift88 ift88 standard conditions Fig. 2 with image from Blanco et al., 2014
Fig. 5 with imageFig. 6 with imageFig. 7 with imageFig. 8 with imageFig. 9 with image from Sukumaran et al., 2009
Reporter gene expression No data available
PHENOTYPE
Phenotype in ift88tz288/tz288
Phenotype Conditions Figures
anterior macula stereocilium bundle bent, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
anterior macula stereocilium bundle splayed, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
blue sensitive photoreceptor cell morphology, abnormal standard conditions Fig. 2 from Krock et al., 2008
cell differentiation occurrence, normal standard conditions Fig. 1 from Krock et al., 2008
cilium assembly decreased process quality, abnormal chemical treatment: prostaglandin E2 Fig. 8 from Jin et al., 2014
cilium assembly decreased process quality, abnormal control Fig. 8 from Jin et al., 2014
cilium assembly disrupted, abnormal standard conditions Fig. 2 with image from Lunt et al., 2009
Fig. 1 from Omori et al., 2008
eye decreased size, abnormal standard conditions Fig. S1 from Krock et al., 2008
eye photoreceptor cell apoptotic, abnormal control Fig. S3 with image from Bachmann-Gagescu et al., 2015
eye photoreceptor cell cilium absent, abnormal standard conditions Fig. 2 from Krock et al., 2008
eye photoreceptor cell nucleus decreased length, abnormal standard conditions Fig. 3 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor connecting cilium absent, abnormal standard conditions Fig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor inner segment membrane disorganized, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor inner segment membrane displaced, abnormal standard conditions Fig. 2 with image from Sukumaran et al., 2009
eye photoreceptor cell photoreceptor outer segment absent, abnormal standard conditions Fig. 1 with imageFig. 2 with imageFig. 3 with image from Sukumaran et al., 2009
hair cell anterior macula normal amount, normal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula apoptotic process increased occurrence, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula cilium decreased length, abnormal control Fig. 8 from Jin et al., 2014
hair cell anterior macula cilium decreased length, abnormal chemical treatment: prostaglandin E2 Fig. 8 from Jin et al., 2014
hair cell anterior macula epithelium organization quality, normal standard conditions Fig. 1 with image from Blanco et al., 2014
hair cell anterior macula stereocilium decreased amount, abnormal standard conditions Fig. 1 with image from Blanco et al., 2014
intraciliary transport disrupted, abnormal standard conditions Fig. 3 from Krock et al., 2008
neural tube axoneme absent, abnormal standard conditions Fig. 2 with image from Lunt et al., 2009
neurocranium morphology, normal standard conditions Fig. 7 with image from Lunt et al., 2009
photoreceptor cell decreased amount, abnormal constant light Fig. 1 with image from Nakao et al., 2012
photoreceptor cell ciliary basal body mislocalised, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
post-vent region curved ventral, abnormal standard conditions Fig. S1 from Krock et al., 2008
pronephros cystic, abnormal standard conditions Fig. S1 from Krock et al., 2008
retina photoreceptor outer segment absent, abnormal standard conditions Fig. 1Fig. 3Fig. 4 from Krock et al., 2008
retinal cone cell absence due to degeneration, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal cone cell decreased amount, abnormal standard conditions Fig. 2 from Feng et al., 2017
Fig. 3 from Pooranachandran et al., 2016
retinal cone cell decreased length, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal cone cell degenerate, abnormal standard conditions Fig. 2 from Feng et al., 2017
retinal cone cell morphology, abnormal standard conditions Fig. 5 with imageFig. 7 with imageFig. 9 with image from Sukumaran et al., 2009
retinal outer nuclear layer perforate, abnormal standard conditions Fig. 1 from Krock et al., 2008
retinal outer nuclear layer eye photoreceptor cell apoptotic, abnormal standard conditions Fig. 1 from Krock et al., 2008
retinal photoreceptor layer apoptotic process increased occurrence, abnormal control Fig. S3 with image from Bachmann-Gagescu et al., 2015
retinal photoreceptor layer eye photoreceptor cell apoptotic, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal rod cell absence due to degeneration, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal rod cell decreased amount, abnormal standard conditions Fig. 3 from Pooranachandran et al., 2016
retinal rod cell morphology, abnormal standard conditions Fig. 2 from Krock et al., 2008
retinal rod cell pigmented, abnormal standard conditions Fig. 1 with image from Nakao et al., 2012
somite cellular quality, normal standard conditions Fig. 9 with image from Lunt et al., 2009
somite shape, normal standard conditions Fig. 9 with image from Lunt et al., 2009
whole organism curved ventral, abnormal standard conditions Fig. S8 with image from Coxam et al., 2014

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