ZFIN Fish: WT + MO1-smad1

ZFIN ID: ZDB-FISH-150901-17306

ZFIN ID: ZDB-FISH-150901-17306

Fish name:	WT + MO1-smad1
Genotype:	WT
Targeting Reagent:	MO1-smad1

HUMAN DISEASE MODELED by WT + MO1-smad1
No data available

GENE EXPRESSION
Gene expression in WT + MO1-smad1

RNA expression

Expressed Gene	Structure	Conditions	Figures
gata1a	blood intermediate cell mass of mesoderm lateral mesoderm	standard conditions	Fig. 4, Fig. 6 from McReynolds et al., 2007
gata2a	lateral mesoderm presumptive ectoderm (not) whole organism	standard conditions	Fig. 3 from Dee et al., 2007 Fig. 4 from McReynolds et al., 2007
hbbe3	nucleate erythrocyte	standard conditions	Fig. 3 from McReynolds et al., 2007
lcp1	(not) blood	standard conditions	Fig. 6 from McReynolds et al., 2007
lmo2	intermediate cell mass of mesoderm lateral mesoderm	standard conditions	Fig. 4, Fig. 6 from McReynolds et al., 2007
mpx	(not) anterior lateral mesoderm	standard conditions	Fig. 6 from McReynolds et al., 2007
myb	(not) intermediate cell mass of mesoderm	standard conditions	Fig. 6 from McReynolds et al., 2007
pax2a	lateral mesoderm	standard conditions	Fig. 5 from McReynolds et al., 2007
runx1	(not) intermediate cell mass of mesoderm	standard conditions	Fig. 6 from McReynolds et al., 2007
sox2	ectoderm presumptive ectoderm	standard conditions	Fig. 3 from Dee et al., 2007
sox3	ectoderm presumptive ectoderm	standard conditions	Fig. 3 from Dee et al., 2007
spi1b	intermediate cell mass of mesoderm	standard conditions	Fig. 4, Fig. 6 from McReynolds et al., 2007
tal1	lateral mesoderm	standard conditions	Fig. 4 from McReynolds et al., 2007
tbxta	mesoderm	standard conditions	Fig. 5 from McReynolds et al., 2007

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO1-smad1

Phenotype	Conditions	Figures
brain morphology, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
cloacal chamber cellular quality, abnormal	standard conditions	Fig. s4 from Laux et al., 2011
ectodermal cell fate commitment disrupted, abnormal	standard conditions	Fig. 3 from Dee et al., 2007
endoderm morphology, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
endoderm formation disrupted, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
epiphysis cellular quality, abnormal	standard conditions	Fig. T1 from Laux et al., 2011
extension morphology, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
heart cellular quality, abnormal	standard conditions	Fig. T1 from Laux et al., 2011
heart shape, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
heart contraction occurrence, normal	standard conditions	Fig. 2 from McReynolds et al., 2007
heart looping arrested, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
median fin fold cellular quality, abnormal	standard conditions	Fig. s4 from Laux et al., 2011
neuroectoderm degenerate, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
notochord increased width, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
otic placode decreased size, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
pharyngeal arch cellular quality, abnormal	standard conditions	Fig. T1 from Laux et al., 2011
somite cellular quality, abnormal	standard conditions	Fig. s4 , Fig. T1 from Laux et al., 2011
tail bud cellular quality, abnormal	standard conditions	Fig. T1 from Laux et al., 2011
whole organism increased length, abnormal	standard conditions	Fig. 2 from McReynolds et al., 2007
whole organism ventralized, abnormal	control	Fig 4 from Watterston et al., 2019
whole organism wholly dorsalized, abnormal	standard conditions	text only from Dee et al., 2007

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