ZFIN ID: ZDB-FISH-150901-15026
Fish name: cdipthi559Tg/hi559Tg
Genotype: cdipthi559Tg/hi559Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by cdipthi559Tg/hi559Tg
No data available
GENE EXPRESSION
Gene expression in cdipthi559Tg/hi559Tg
Reporter gene expression No data available
PHENOTYPE
Phenotype in cdipthi559Tg/hi559Tg
Phenotype Conditions Figures
apoptotic process increased occurrence, abnormal standard conditions Fig. 5 from Murphy et al., 2011
apoptotic process occurrence, normal standard conditions Fig. 5 from Murphy et al., 2011
enteroendocrine cell autophagosome increased amount, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
eye decreased size, abnormal standard conditions Fig. 3 from Murphy et al., 2011
eye photoreceptor cell chromatin condensed, abnormal standard conditions Fig. 2 from Murphy et al., 2011
forebrain decreased width, abnormal standard conditions Fig. S2 with image from Blaker-Lee et al., 2012
goblet cell detached from intestinal epithelium, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
goblet cell disorganized, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
goblet cell increased amount, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
goblet cell increased amount, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
goblet cell increased amount, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
goblet cell mislocalised, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
goblet cell normal amount, normal chemical treatment: sodium phenylbutyrate Fig. 7 with image from Thakur et al., 2014
goblet cell condensed nuclear chromosome increased amount, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
goblet cell cytoskeleton disorganized, abnormal standard conditions Fig. S2 with image from Thakur et al., 2014
goblet cell exocytic vesicle morphology, abnormal standard conditions Fig. S2 with image from Thakur et al., 2014
intestinal epithelial cell apoptotic, abnormal standard conditions Fig. 3 with imageFig. 7 with imageFig. S2 with image from Thakur et al., 2014
intestinal epithelial cell apoptotic, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell apoptotic, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell apoptotic, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell detached from intestinal epithelium, abnormal standard conditions Fig. 1 with imageFig. 2 with imageFig. S2 with image from Thakur et al., 2014
intestinal epithelial cell disorganized, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Thakur et al., 2014
intestinal epithelial cell shape, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Thakur et al., 2014
intestinal epithelial cell autophagosome increased amount, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagosome increased amount, abnormal standard conditions Fig. 4 with imageFig. S5 with image from Thakur et al., 2014
intestinal epithelial cell autophagosome increased amount, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagosome increased amount, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagy increased occurrence, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagy increased occurrence, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagy increased occurrence, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestinal epithelial cell autophagy increased occurrence, abnormal standard conditions Fig. S5 with image from Thakur et al., 2014
intestinal epithelial cell autophagy of mitochondrion increased process quality, abnormal standard conditions Fig. 4 with imageFig. S5 with image from Thakur et al., 2014
intestinal epithelial cell brush border atrophied, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
intestinal epithelial cell brush border decreased thickness, abnormal standard conditions Fig. S2 with image from Thakur et al., 2014
intestinal epithelial cell brush border morphology, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
intestinal epithelial cell cell population proliferation decreased process quality, abnormal standard conditions Fig. 3 with image from Thakur et al., 2014
intestinal epithelial cell cortical actin cytoskeleton decreased thickness, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
intestinal epithelial cell cytoplasm immature, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
intestinal epithelial cell endoplasmic reticulum distended, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
intestinal epithelial cell endoplasmic reticulum lumen distended, abnormal standard conditions Fig. S5 with image from Thakur et al., 2014
intestinal epithelial cell endoplasmic reticulum lumen vacuolated, abnormal standard conditions Fig. S5 with image from Thakur et al., 2014
intestinal epithelial cell Golgi apparatus distended, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
intestinal epithelial cell mitochondrion decreased amount, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
intestinal epithelial cell mitochondrion morphology, abnormal standard conditions Fig. 4 with image from Thakur et al., 2014
intestinal epithelial cell positive regulation of autophagy in response to ER overload increased process quality, abnormal standard conditions Fig. S5 with image from Thakur et al., 2014
intestinal epithelial cell vesicle increased amount, abnormal standard conditions Fig. S2 with image from Thakur et al., 2014
intestinal epithelial cell vesicle increased size, abnormal standard conditions Fig. 2 with imageFig. 4 with imageFig. S2 with image from Thakur et al., 2014
intestinal epithelium decreased thickness, abnormal standard conditions Fig. 3 with image from Thakur et al., 2014
intestinal villus damage, abnormal standard conditions Fig. 1 with imageFig. 2 with imageFig. 7 with image from Thakur et al., 2014
intestine decreased size, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestine decreased size, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestine decreased size, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestine decreased size, abnormal chemical treatment: sodium phenylbutyrate Fig. 7 with image from Thakur et al., 2014
intestine decreased size, abnormal standard conditions Fig. 1 with imageFig. 7 with imageFig. S1 with image from Thakur et al., 2014
intestine decreased volume, abnormal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestine decreased volume, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestine decreased volume, abnormal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestine decreased volume, abnormal standard conditions Fig. 1 with imageFig. 7 with imageFig. S1 with image from Thakur et al., 2014
intestine decreased volume, abnormal chemical treatment: sodium phenylbutyrate Fig. 7 with image from Thakur et al., 2014
intestine leukocyte increased amount, abnormal chemical treatment: streptomycin, chemical treatment: penicillin, chemical treatment: ampicillin, chemical treatment: kanamycin Fig. 6 with image from Thakur et al., 2014
intestine leukocyte increased amount, abnormal control Fig. 7 with image from Thakur et al., 2014
intestine leukocyte normal amount, normal chemical treatment: pharmaceutical, chemical treatment: drug Fig. 6 with image from Thakur et al., 2014
intestine leukocyte normal amount, normal chemical treatment: mesalamine, chemical treatment: 6alpha-methylprednisolone Fig. 6 with image from Thakur et al., 2014
intestine mucus layer decreased thickness, abnormal standard conditions Fig. 2 with imageFig. S2 with image from Thakur et al., 2014
lens decreased size, abnormal standard conditions Fig. 1 from Murphy et al., 2011
lens degenerate, abnormal standard conditions Fig. 1 from Murphy et al., 2011
lens morphology, normal standard conditions Fig. 2 from Murphy et al., 2011
lens cell apoptotic, abnormal standard conditions Fig. 5 from Murphy et al., 2011
lens cell disorganized, abnormal standard conditions Fig. 1Fig. 4 from Murphy et al., 2011
lens cell poorly differentiated, abnormal standard conditions Fig. 3 from Murphy et al., 2011
lens epithelium columnar/cuboidal epithelial cell disorganized, abnormal standard conditions Fig. 1Fig. 3 from Murphy et al., 2011
lens epithelium columnar/cuboidal epithelial cell shape, abnormal standard conditions Fig. 3 from Murphy et al., 2011
lens epithelium epithelial cell organized, normal standard conditions Fig. 2 from Murphy et al., 2011
mid intestine goblet cell decreased amount, abnormal standard conditions Fig. S2 with image from Thakur et al., 2014
mid intestine goblet cell normal amount, normal standard conditions Fig. S2 with image from Thakur et al., 2014
pancreatic acinar cell endoplasmic reticulum lumen distended, abnormal standard conditions Fig. S5 with image from Thakur et al., 2014
response to bacterium disrupted, abnormal standard conditions Fig. 2 with image from Thakur et al., 2014
retina layer formation disrupted, abnormal standard conditions Fig. 1 from Murphy et al., 2011
retinal photoreceptor layer aplastic, abnormal standard conditions Fig. 1 from Murphy et al., 2011
retinal photoreceptor layer has fewer parts of type retinal rod cell, abnormal standard conditions Fig. 4 from Murphy et al., 2011
retinal photoreceptor layer lacks all parts of type retinal cone cell, abnormal standard conditions Fig. 3 from Murphy et al., 2011
retinal photoreceptor layer lacks all parts of type retinal rod cell, abnormal standard conditions Fig. 3 from Murphy et al., 2011
retinal photoreceptor layer lacks parts or has fewer parts of type retinal cone cell, abnormal standard conditions Fig. 4 from Murphy et al., 2011
retinal photoreceptor layer eye photoreceptor cell apoptotic, abnormal standard conditions Fig. 5 from Murphy et al., 2011
retinal photoreceptor layer retinal cone cell disorganized, abnormal standard conditions Fig. 2 from Murphy et al., 2011
retinal photoreceptor layer retinal rod cell disorganized, abnormal standard conditions Fig. 2 from Murphy et al., 2011
ventricular system decreased size, abnormal standard conditions Fig. S2 with image from Blaker-Lee et al., 2012
whole organism dead, abnormal standard conditions Fig. 1 with image from Thakur et al., 2014

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