ZFIN ID: ZDB-FISH-150901-14828
Fish name: noton1/n1
Genotype: noton1/n1
Targeting Reagent: none

HUMAN DISEASE MODELED by noton1/n1
No data available
GENE EXPRESSION
Gene expression in noton1/n1
Expressed Gene Structure Conditions Figures
aanat2 (not) pineal complex control Fig. 3 from Gamse et al., 2002
Fig. 4 from Gothilf et al., 1999
agrp hypothalamus standard conditions Fig. 5 from Zhang et al., 2010
alcama floor plate spinal cord region, motor neuron axon, spinal cord secondary motor neuron standard conditions Fig. 1 with imageFig. 2 with image from Beattie et al., 1997
ascl1a epiphysis standard conditions Fig. 1 with image from Khuansuwan et al., 2016
asip2b (not) epiphysis standard conditions Fig. 5 from Zhang et al., 2010
col2a1a floor plate neural tube, floor plate spinal cord region, (not) notochord standard conditions Fig. 2 with imageFig. 3 with image from Beattie et al., 1997
fn1a endocardial precursor standard conditions Fig. 9 with image from Wong et al., 2012
foxd3 neural crest standard conditions Fig. 5 with image from Nguyen et al., 2000
gfi1ab parapineal organ neuron standard conditions Fig. 3 with image from Khuansuwan et al., 2016
Fig. 3 with image from Snelson et al., 2008
isl2a CaP motoneuron, Rohon-Beard neuron, VaP motor neuron standard conditions Fig. 3 with image from Beattie et al., 1997
kctd12.1 habenula standard conditions Fig. 3 with image from Snelson et al., 2008
kdrl endocardial precursor standard conditions Fig. 9 with image from Wong et al., 2012
lhx3 hypophysis, spinal cord standard conditions Fig. 5 with imageFig. 6 with image from Glasgow et al., 1997
myf5 adaxial cell, paraxial mesoderm, segmental plate (all 4) expand standard conditions Fig. 4 with image from Coutelle et al., 2001
myod1 adaxial cell, somite, tail bud standard conditions Fig. 4 with image from Coutelle et al., 2001
nfatc1 endocardium standard conditions Fig. 9 with image from Wong et al., 2012
noto epiphysis standard conditions Fig. 2 from Gamse et al., 2002
nr2e3 epiphysis standard conditions Fig. 1 with image from Khuansuwan et al., 2016
otx5 parapineal organ standard conditions Fig. 2 from Gamse et al., 2002
pmch hypothalamus standard conditions Fig. 5 from Zhang et al., 2010
pmchl hypothalamus standard conditions Fig. 5 from Zhang et al., 2010
pomca hypothalamus standard conditions Fig. 5 from Zhang et al., 2010
shha axial mesoderm, neural crest, (not) notochord (all 5) expand standard conditions Fig. 5 with image from Nguyen et al., 2000
Fig. 5 with imageFig. 6 with image from Beattie et al., 1997
shhb presumptive floor plate standard conditions Fig. 7 with image from Beattie et al., 1997
sox1a parapineal organ neuron standard conditions Fig. 3 with image from Khuansuwan et al., 2016
ta axial mesoderm standard conditions Fig. 6 with image from Dheen et al., 1999
tbx2b (not) axial mesoderm, epiphysis, pineal complex (all 4) expand standard conditions Fig. 1 with image from Khuansuwan et al., 2016
Fig. 4 with image from Snelson et al., 2008
Fig. 6 with image from Dheen et al., 1999
tlx3b Rohon-Beard neuron, trigeminal placode standard conditions Fig. 5 with image from Nguyen et al., 2000
vgll2b (not) adaxial cell, (not) notochord standard conditions Fig. 3 with image from Mann et al., 2007
PHENOTYPE 
Phenotype in noton1/n1
Phenotype Conditions Figures
adaxial cell immature, abnormal standard conditions Fig. 4 with image from Coutelle et al., 2001
adaxial cell mislocalised, abnormal standard conditions Fig. 6 with image from Yin et al., 2007
Fig. 4 with image from Coutelle et al., 2001
axial mesoderm development disrupted, abnormal standard conditions Fig. 5 with image from Beattie et al., 1997
endocardium morphogenesis disrupted, abnormal standard conditions Fig. 9 with image from Wong et al., 2012
epiphysis nr2e3 expression decreased amount, abnormal standard conditions Fig. 1 with image from Khuansuwan et al., 2016
epiphysis tbx2b expression decreased amount, abnormal standard conditions Fig. 1 with image from Khuansuwan et al., 2016
floor plate split, abnormal standard conditions Fig. 2 with imageFig. 6 with image from Beattie et al., 1997
hypophysis increased size, abnormal standard conditions Fig. 6 with image from Glasgow et al., 1997
hypophysis cell increased amount, abnormal standard conditions Fig. 6 with image from Glasgow et al., 1997
melanocyte distended, abnormal standard conditions Fig. 5 from Zhang et al., 2010
notochord absent, abnormal standard conditions Fig. 6 with image from Dheen et al., 1999
parapineal organ has extra parts of type parapineal organ neuron, abnormal standard conditions Fig. 3 with image from Khuansuwan et al., 2016
parapineal organ neuron fate specification increased occurrence, abnormal standard conditions Fig. 3 with image from Khuansuwan et al., 2016
pineal complex aanat2 expression absent, abnormal control Fig. 4 from Gothilf et al., 1999
pineal complex decreased size, abnormal standard conditions Fig. 3 from Gamse et al., 2002
pineal gland development process quality, abnormal standard conditions Fig. 3 with image from Khuansuwan et al., 2016
secondary motor neuron anatomical region discontinuous, abnormal standard conditions Fig. 1 with image from Beattie et al., 1997
secondary motor neuron anatomical region split, abnormal standard conditions Fig. 2 with image from Beattie et al., 1997
secondary motor neuron axon morphology, abnormal standard conditions Fig. 1 with image from Beattie et al., 1997
spinal cord has fewer parts of type primary motor neuron, abnormal standard conditions Fig. 3 with imageFig. 4 from Beattie et al., 1997
spinal cord posterior region lacks all parts of type primary motor neuron, abnormal standard conditions Fig. 4 from Beattie et al., 1997
striated muscle cell differentiation delayed, abnormal standard conditions Fig. 4 with image from Coutelle et al., 2001
whole organism lacks all parts of type notochord, abnormal standard conditions Fig. 3 with imageFig. 6 with image from Beattie et al., 1997

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