ZFIN ID: ZDB-FISH-150901-13939
Fish name: i113Tg
Genotype: i113Tg
Targeting Reagent: none

HUMAN DISEASE MODELED by i113Tg
Human Disease Conditions Citations
lung disease chemical treatment by injection: lipopolysaccharide Zhang et al., 2016
GENE EXPRESSION
Gene expression in i113Tg
Expressed Gene Structure Conditions Figures
GFP myeloid cell, neutrophil control Fig. 1 with imageFig. 4 with image from Zhang et al., 2016
Fig. 1Fig. 2Fig. 4 from Li et al., 2011
blood vessel, capillary, neutrophil chemical treatment by injection: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, chemical treatment by injection: lipopolysaccharide Fig. 1 with imageFig. 4 with image from Zhang et al., 2016
il1b anatomical structure, swim bladder chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
il6 anatomical structure, swim bladder chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
tnfb anatomical structure, swim bladder chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
PHENOTYPE 
Phenotype in i113Tg
Phenotype Conditions Figures
anatomical structure il1b expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
anatomical structure tnfb expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
anatomical structure il6 expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
neutrophil accumulation swim bladder, ameliorated chemical treatment by environment: 2-(2-amino-3-methoxyphenyl)chromen-4-one, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil accumulation swim bladder, ameliorated chemical treatment by environment: LY294002, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil accumulation swim bladder, ameliorated chemical treatment by environment: anthra[1,9-cd]pyrazol-6(2H)-one, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil accumulation swim bladder, ameliorated chemical treatment by injection: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil increased accumulation swim bladder, abnormal chemical treatment by injection: lipopolysaccharide Fig. 1 with imageFig. 4 with image from Zhang et al., 2016
neutrophil chemotaxis increased occurrence, abnormal chemical treatment by injection: silicon dioxide nanoparticle Fig. 1 with image from Zhang et al., 2016
neutrophil chemotaxis increased occurrence, abnormal chemical treatment by injection: poly(I:C) Fig. 1 with image from Zhang et al., 2016
neutrophil chemotaxis increased occurrence, abnormal chemical treatment by injection: lipopolysaccharide Fig. 1 with imageFig. 4 with image from Zhang et al., 2016
neutrophil chemotaxis occurrence, ameliorated chemical treatment by injection: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil chemotaxis occurrence, ameliorated chemical treatment by environment: LY294002, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil chemotaxis occurrence, ameliorated chemical treatment by environment: anthra[1,9-cd]pyrazol-6(2H)-one, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
neutrophil chemotaxis occurrence, ameliorated chemical treatment by environment: 2-(2-amino-3-methoxyphenyl)chromen-4-one, chemical treatment by injection: lipopolysaccharide Fig. 4 with image from Zhang et al., 2016
swim bladder il6 expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder tnfb expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder il1b expression increased amount, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder endoplasmic reticulum swollen, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder epithelium broken, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder mitochondrial crista broken, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016
swim bladder mitochondrion vacuolated, abnormal chemical treatment by injection: lipopolysaccharide Fig. 3 with image from Zhang et al., 2016

CITATIONS  (11)