Engineered Foreign Gene

GtACR1

ID
ZDB-EFG-200519-1
Name
GtACR1
Symbol
GtACR1
Previous Names
None
Type
engineered_foreign_gene
Location
Unmapped
Note
Light-regulated neuron inhibition tool. GtACR1 corresponds to the light-gated anion channel encoded by the Guillardia theta ACR1 gene (GB_protein:XP_005829297). It can be used as an optogenetic tool to produce membrane hyperpolarization and inhibit neuron activity; it strictly conducts anions, shows rapid response kinetics, and requires low light intensity for activation. The maximal sensitivity of the protein is to 515nm light (PMID:26113638).
Expression
All Expression Data
No data available
Constructs
Antibodies
No data available
Sequence Information
Citations
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