CRISPR

CRISPR2-elovl6

ID

ZDB-CRISPR-201026-1

Name

CRISPR2-elovl6

Previous Names

None

Target

elovl6 (1)

Sequence

5' - TACGCTGCCTGCATACTCGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3197	elovl6

Expression

Gene expression in Wild Types + CRISPR2-elovl6

No data available

Phenotype

Phenotype resulting from CRISPR2-elovl6

No data available

Phenotype of all Fish created by or utilizing CRISPR2-elovl6

Phenotype	Fish	Conditions	Figures
liver fasn expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver pck2 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver lpla expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver acsbg2 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver gck expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
whole organism lipid increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. 1 from Wang et al., 2020
liver gys2 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver ucp1 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
blood glucose decreased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	fasting	Fig. 1 from Wang et al., 2020
fatty acid elongation disrupted, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. 1 from Wang et al., 2020
whole organism fatty acid composition, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. 1 from Wang et al., 2020
liver hkdc1 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver slc27a1b expression decreased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020
liver ucp2 expression increased amount, abnormal	elovl6^{zf3197/zf3197} (AB)	standard conditions	Fig. S2 from Wang et al., 2020

Citations