CRISPR

CRISPR1-foxp3a

ID

ZDB-CRISPR-200723-4

Name

CRISPR1-foxp3a

Previous Names

None

Target

foxp3a (1)

Sequence

5' - GGCCAGTCTGAAAGCAGAAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ihb419	foxp3a

Expression

Gene expression in Wild Types + CRISPR1-foxp3a

No data available

Phenotype

Phenotype resulting from CRISPR1-foxp3a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-foxp3a

Phenotype	Fish	Conditions	Figures
testis mpeg1.1 expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 7 from Li et al., 2020
gonad cyp19a1a expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
oocyte stage IV decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
testis ifng1r expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5, Fig. 7 from Li et al., 2020
male organism decreased weight, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
ovary decreased size, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
testis gsdf expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis insl3 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis Ab36-h3 labeling decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis gsdf expression increased distribution, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis cyp17a1 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis dazl expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
female organism decreased length, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
testis structure, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
testis nanos2 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
gonad ifng1r expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
testis hsd3b2 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
spermatogonium increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
male gonad development disrupted, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
testis tnfa expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5, Fig. 7 from Li et al., 2020
spermatocyte increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
testis cyp11c1 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
sperm decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
testis apoptotic, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5, Fig. 6 from Li et al., 2020
testis dnd1 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
male organism decreased length, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
female organism decreased weight, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
testis Ab2-sycp3 labeling decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis il6 expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 7 from Li et al., 2020
testis lck expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 7 from Li et al., 2020
testis present, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
gonad dmrt1 expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
male gonad development delayed, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
testis insl3 expression increased distribution, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis amh expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis mitotic cell cycle decreased occurrence, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
testis ddx4 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5, Fig. 6 from Li et al., 2020
testis male meiotic nuclear division decreased occurrence, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
oocyte stage III absent, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
oocyte degeneration, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
oocyte stage III decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 4 from Li et al., 2020
ovulation decreased rate, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
gonad tnfa expression increased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
testis decreased size, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3 from Li et al., 2020
female gonad development disrupted, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 3, Fig. 4 from Li et al., 2020
testis nanos3 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
gonad ddx4 expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
testis zbtb16a expression decreased amount, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 6 from Li et al., 2020
gonad apoptotic, abnormal	foxp3a^{ihb419/ihb419} (AB)	standard conditions	Fig. 5 from Li et al., 2020
testis T cell increased amount, abnormal	foxp3a^{ihb419/ihb419}; cz2Tg (AB)	standard conditions	Fig. 7 from Li et al., 2020
testis macrophage increased amount, abnormal	foxp3a^{ihb419/ihb419}; ihb20Tg (AB)	standard conditions	Fig. 7 from Li et al., 2020

Citations