cysteine-type endopeptidase activity involved in apoptotic process

Term ID

GO:0097153

Synonyms

caspase activity
metacaspase activity

Definition

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.

References

Reactome:R-HSA-6800797

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is part of: apoptotic process

apoptotic process Show first 5 Terms
is a type of: cysteine-type endopeptidase activity

cysteine-type endopeptidase activity Show first 5 Terms
has subtype: cysteine-type endopeptidase activity involved in apoptotic signaling pathway cysteine-type endopeptidase activity involved in execution phase of apoptosis

cysteine-type endopeptidase activity involved in apoptotic signaling pathway cysteine-type endopeptidase activity involved in execution phase of apoptosis Show first 5 Terms
negatively regulated by: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Show first 5 Terms
positively regulated by: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Show first 5 Terms
regulated by: regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity involved in apoptotic process Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations