Notch signaling pathway

Term ID

GO:0007219

Synonyms

N signaling pathway
N signalling pathway
Notch receptor signaling pathway
Notch receptor signalling pathway
Notch signalling pathway
Notch-receptor signaling pathway
Notch-receptor signalling pathway

Definition

The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

References

Wikipedia:Notch_signaling_pathway

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: Notch receptor processing, ligand-dependent positive regulation of transcription of Notch receptor target

Notch receptor processing, ligand-dependent positive regulation of transcription of Notch receptor target Show first 5 Terms
is a type of: cell surface receptor signaling pathway

cell surface receptor signaling pathway Show first 5 Terms
has subtype: Notch signaling involved in heart development Notch signaling pathway involved in arterial endothelial cell fate commitment Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Notch signaling pathway involved in forebrain neuroblast division Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment ... Show All 7 Terms

Notch signaling involved in heart development Notch signaling pathway involved in arterial endothelial cell fate commitment Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Notch signaling pathway involved in forebrain neuroblast division Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation Notch signaling pathway involved in somitogenesis Show first 5 Terms
negatively regulated by: negative regulation of Notch signaling pathway

negative regulation of Notch signaling pathway Show first 5 Terms
positively regulated by: positive regulation of Notch signaling pathway

positive regulation of Notch signaling pathway Show first 5 Terms
regulated by: regulation of Notch signaling pathway

regulation of Notch signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations