Search Ontology:
GO: Biological Process

double-strand break repair via nonhomologous end joining

Term ID
GO:0006303
Synonyms
  • NHEJ
Definition
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
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negatively regulated by
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Phenotype
Phenotype caused by Genes