Search Ontology:
GO: Biological Process

double-strand break repair via homologous recombination

Term ID
GO:0000724
Synonyms
  • HDR
  • homologous recombinational repair
  • homology-directed repair
  • HRR
  • Rad51-dependent recombinational repair
  • Rhp51-dependent recombinational repair
Definition
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. 10357855
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
has parts
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes
Citations