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Human Disease

breast large cell neuroendocrine carcinoma

Term ID
DOID:6657
Synonyms
Definition
A breast carcinoma that is characterized by large cell size, polygonal shape, low nuclear-cytoplasmic ratio, finely granular eosinophilic cytoplasm, occasionally prominent nucleoli, peripheral palisading, mitosis, and necrosis and in which greater than 50% of the tumor cells are positive for neuroendocrine markers (NSE, chromogranin A, synaptophysin). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608661/
References
  • NCI:C40356
  • UMLS_CUI:C1511316
Ontology
Human Disease   ( DOID:6657 )
Relationships
is a type of
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Genes Involved
Zebrafish Models