OBO ID: DOID:12177
Term Name: common variable immunodeficiency Search Ontology:
Synonyms:
  • acquired agammaglobulinemia
  • acquired hypogammaglobulinemia
  • common variable agammaglobulinemia
  • CVID
  • sporadic hypogammaglobulinemia
Definition: An agammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. (2)
References:
Ontology: Human Disease   (DOID:12177)
OTHER common variable immunodeficiency PAGES
GENES INVOLVED
Human Gene Zebrafish Ortholog OMIM Term OMIM Phenotype ID
CD81 Immunodeficiency, common variable, 6 613496
IL21 ?Immunodeficiency, common variable, 11 615767
LRBA Immunodeficiency, common variable, 8, with autoimmunity 614700
NFKB2 Immunodeficiency, common variable, 10 615577
CD19 Immunodeficiency, common variable, 3 613493
CR2 Immunodeficiency, common variable, 7 614699
ICOS Immunodeficiency, common variable, 1 607594
MS4A1 ?Immunodeficiency, common variable, 5 613495
TNFRSF13B Immunodeficiency, common variable, 2 240500
TNFRSF13C Immunodeficiency, common variable, 4 613494
ZEBRAFISH MODELS No data available
PHENOTYPE No data available

CITATIONS: None