ST2 diffuse large B-cell lymphoma

Term ID

DOID:0081068

Synonyms

• ST2 DLBCL

Definition

A diffuse large B-cell lymphoma that is categorized as ST2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and ST2 DLBCLs often, but do not always, have missense or nonsense mutations affecting TET2 and NFKBIA. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting some combination of SGK1, ZFP36L1, SOCS1, HIST1H1E and CD83, which can be coding or non-coding. (2)

References

Ontology

Human Disease   ( DOID:0081068 )