- Title
-
Centella asiatica extract ameliorates deoxygenation-induced neurological dysfunction in zebrafish larvae
- Authors
- Ariani, A., Khotimah, H., Sulistyarini, A., Daniaridevi, A.S.
- Source
- Full text @ Open Vet J
BDNF expression of embryonic zebrafish at 3, and 9 dpf in the treatment groups. Data are shown as the mean ± SD. The administration of CA with varying concentrations under OD conditions showed a significant difference in BDNF expression (p < 0.001). Still, there was no difference in BDNF expression based on the duration of administration (3 dpf and 9 dpf). There was no interaction between the treatment and the duration of administration. * (p < 0.05), dan ** (p < 0.01). |
VGLUT1 expression of embryonic zebrafish at 3, and 9 dpf in the CA treatment groups under OD conditions. There was no significant difference in VGLUT1 gene expression with the timing of CA administration (ages 3 dpf and 9 dpf), and an interaction occurred between the treatment and the timing of CA administration (p > 0.05). A significant difference in VGLUT1 gene expression was caused by the concentration of CA treatment (p < 0.05). The administration of CA at a concentration of 2.5 μg/ml. **** (p < 0.0001) dan ns (not significance). |