FIGURE SUMMARY
Title

Green honey of Banggi Island: A preliminary anti-diabetic study on zebrafish model

Authors
Ullah, S., Huyop, F., Huda, N., Ab Wahab, R., Hamid, A.A.A., Mohamad, M.A.N., Ahmad, H.F., Shariff, A.H.M., Nasir, M.H.M.
Source
Full text @ Heliyon

Raw green honey collected from Banggi Island, Sabah. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

The timeline of the diabetic induction using two doses of STZ on days 7 and 9 with excess feeding regime.

Force feeding (Oral administration) of GH, acarbose and sucrose.

The changes of body weight between the Non-DM and DM, groups at pre- and post-induction of diabetes using excess diet and STZ.

The differences of the fasting blood glucose level between the non-DM and DM groups during pre- and post-induction of diabetes. (n = 24, paired t-test).

The effect of GH treatment and acarbose on Oral Sucrose Tolerance Test (OSTT) treatment was orally administered to zebrafish for 30 min before sucrose loading. The postprandial blood glucose level was observed for 2.5 h, are presented as mean ± SEM, with a sample size of n = 15. A nonparametric t-test was employed to assess significant differences between various groups at distinct time intervals. Significance levels were denoted as follows: ****p < 0.0001, indicating variations in means when compared to the control group of healthy, non-diabetic zebrafish.

Area under the curve (AUC) of the zebrafish blood glucose level after oral sucrose administration. Data are expressed as mean ± SEM. One-way analysis of variance (ANOVA) was used to carry out the significant differences with a t-test using Dunnett's Multiple Comparison. The significant difference was considered at ***p < 0.001 between the means of groups compared to the control normal healthy group.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Heliyon