FIGURE SUMMARY
Title

Immunopathogenesis of Emerging Candida auris and Candida haemulonii Strains

Authors
Pharkjaksu, S., Boonmee, N., Mitrpant, C., Ngamskulrungroj, P.
Source
Full text @ J Fungi (Basel)
Figure 1

Differing thermotolerances of Candida albicans, C. auris, and C. haemulonii. Sabouraud dextrose agar plates showing growth of representative Candida strains after 48 h incubation at 30–42 °C with serial dilution spots. Top row: C. albicans ATCC24433 as the control strain; middle row: C. auris strain SI-18-CAU-HEM; and bottom row: C. haemulonii strain SI-21-CH-PLF.
Figure 2

Emerging Candida virulence in a zebrafish model. Each experimental group of 26 zebrafish was injected with 107 CFU cells of one of the C. albicans ATCC24433 (control) strain, C. auris strain SI-18-CAU-HEM, or C. haemulonii strain SI-21-CH-PLF. Each experiment was performed in duplicate.
Figure 3

Fungal burden in zebrafish model. Each experimental group of five zebrafish was injected with 107 cells of one of the C. albicans ATCC24433 (control) strain, C. auris strain SI-18-CAU-HEM, and C. haemulonii strain SI-21-CH-PLF. Each experiment was performed in triplicate. Abbreviations and symbols: CFU/mL, colony forming unit per milliliter; ****, p < 0.0001.
Figure 4

The expression levels of il1b, il10, il17a, mmp9, foxp3a, and foxp3b in zebrafish infected with emerging Candida strains, by timepoint. Each experimental group of 20 zebrafish was injected with 107 CFU cells of one of the C. auris strain SI-18-CAU-HEM or the C. haemulonii strain SI-21-CH-PLF. The normalized ratios of expression were calculated by comparison with the level of expression of the β-actin gene in each group at 8 hpi. Each experiment was performed in triplicate. Abbreviations and symbols: hpi, hour-post-infection; *, p < 0.5; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Fungi (Basel)
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.