FIGURE SUMMARY
Title

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Authors
Chang, T.C., Wei, P.L., Makondi, P.T., Chen, W.T., Huang, C.Y., Chang, Y.J.
Source
Full text @ PLoS One
Fig. 2

The inhibitory effect of bromelain on colorectal cancer growth was confirmed using a xenotransplantation assay performed in a zebrafish system. (A) In HCT116 cells, the percentage of cells in embryos decreased after exposure to bromelain from 72% (vehicle) to 47% (100 μg/ml) and 18% (300 μg/ml). An increase in the percentage of cells in embryos was found from 22% (vehicle) to approximately 82% (bromelain). (B) In DLD-1 cells, an increase in the percentage of cells in embryo was found from 6% (vehicle) to approximately 94% (bromelain). The figure is representative of the fluorescence intensity in embryos. Data are presented as the mean±SD. ** p<0.001.

PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Day 5
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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