ZFIN Image: Chang et al., 2019, Fig. 2

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Fig. 2

The inhibitory effect of bromelain on colorectal cancer growth was confirmed using a xenotransplantation assay performed in a zebrafish system. (A) In HCT116 cells, the percentage of cells in embryos decreased after exposure to bromelain from 72% (vehicle) to 47% (100 μg/ml) and 18% (300 μg/ml). An increase in the percentage of cells in embryos was found from 22% (vehicle) to approximately 82% (bromelain). (B) In DLD-1 cells, an increase in the percentage of cells in embryo was found from 6% (vehicle) to approximately 94% (bromelain). The figure is representative of the fluorescence intensity in embryos. Data are presented as the mean±SD. ** p<0.001.

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Acknowledgments

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