FIGURE SUMMARY
- Title
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A novel molecular rotor facilitates detection of p53-DNA interactions using the Fluorescent Intercalator Displacement Assay
- Authors
- Goh, W.L., Lee, M.Y., Lim, T.X., Chua, J.S., Brenner, S., Ghadessy, F.J., Teo, Y.N.
- Source
- Full text @ Sci. Rep.
In-vivo staining of live zebrafish embryos using compound AO-R. (a) Live imaging of either wildtype (top panels), or Mdm?/? (bottom panels) 1?day post fertilization zebrafish embryos stained using either AO-C (left panels) or AO-R (right panels) dyes. Scale bars measure 1?mm. (b) Fluorescence intensity of individually measured whole, wildtype or Mdm2 knock-out, zebrafish embryos stained with either AO-C or AO-R dyes. (N?=?22; *P?<?0.0001, unpaired, two-tailed student t test). |
Acknowledgments
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Full text @ Sci. Rep.