FIGURE SUMMARY
- Title
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Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration
- Authors
- Tan, P.L., Garrett, M.E., Willer, J.R., Campochiaro, P.A., Campochiaro, B., Zack, D.J., Ashley-Koch, A.E., Katsanis, N.
- Source
- Full text @ Invest. Ophthalmol. Vis. Sci.
Zebrafish in vivo analysis of variants. (A) Representative images of the hyaloid vessels in 5dpf fli1:EGFP zebrafish. (B) Comparison of the overexpression of wild-type and mutant encoding human mRNA hyaloid vessel diameter normalized to wild-type. *P < 0.01 for green and orange bars (bars with stripes, positive and negative control; blue bars, benign; green bars, hypoactive allele; orange bar, hyperactive allele). Error bars represent standard error. |
Acknowledgments
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Full text @ Invest. Ophthalmol. Vis. Sci.