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Fig. 2
Zebrafish in vivo analysis of variants. (A) Representative images of the hyaloid vessels in 5dpf fli1:EGFP zebrafish. (B) Comparison of the overexpression of wild-type and mutant encoding human mRNA hyaloid vessel diameter normalized to wild-type. *P < 0.01 for green and orange bars (bars with stripes, positive and negative control; blue bars, benign; green bars, hypoactive allele; orange bar, hyperactive allele). Error bars represent standard error.