ZFIN ID: ZDB-PERS-110520-1
Giacomotto, Jean
Email: giacomottojean@gmail.com
URL: http://https://sites.google.com/site/giacomottojean/areas-of-interest
Affiliation: Psychiatric Genomics, Prof. Bryan Mowry laboratory
Address: Queensland Brain Institute The University of Queensland - St Lucia Honorary affiliate of Sydney Medical School Brain & Mind Research Institute
Phone: +61 2 9114 4208
Orcid ID:


Lim, Y.W., Lo, H.P., Ferguson, C., Martel, N., Giacomotto, J., Gomez, G.A., Yap, A.S., Hall, T.E., Parton, R.G. (2017) Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development. Current biology : CB. 27(13):1968-1981.e7
Giacomotto, J., Carroll, A.P., Rinkwitz, S., Mowry, B., Cairns, M.J., Becker, T.S. (2016) Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Translational psychiatry. 6:e818
Svahn, A.J., Giacomotto, J., Graeber, M.B., Rinkwitz, S., Becker, T.S. (2016) miR-124 contributes to the functional maturity of microglia. Developmental Neurobiology. 76(5):507-18
Laird, A.S., Mackovski, N., Rinkwitz, S., Becker, T.S., Giacomotto, J. (2016) Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages. Human Molecular Genetics. 25(9):1728-38
Ishibashi, M., Manning, E., Shoubridge, C., Krecsmarik, M., Hawkins, T.A., Giacomotto, J., Zhao, T., Mueller, T., Bader, P.I., Cheung, S.W., Stankiewicz, P., Bain, N.L., Hackett, A., Reddy, C.C., Mechaly, A.S., Peers, B., Wilson, S.W., Lenhard, B., Bally-Cuif, L., Gecz, J., Becker, T.S., Rinkwitz, S. (2015) Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene. Human genetics. 134(11-12):1163-82
Himaya, S.W., Jin, A.H., Dutertre, S., Giacomotto, J., Mohialdeen, H., Vetter, I., Alewood, P.F., Lewis, R.J. (2015) Comparative venomics reveals the complex prey capture strategy of the piscivorous cone snail Conus catus. Journal of Proteome Research. 14(10):4372-81
Giacomotto, J., Rinkwitz, S., Becker, T.S. (2015) Effective heritable gene knockdown in zebrafish using synthetic microRNAs. Nature communications. 6:7378
Punnamoottil, B., Rinkwitz, S., Giacomotto, J., Svahn, A.J., Becker, T.S. (2015) Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of SLIT2/3 genes. Genesis (New York, N.Y. : 2000). 53(5):321-8
Giacomotto, J., Brouilly, N., Walter, L., Mariol, M.C., Berger, J., Ségalat, L., Becker, T.S., Currie, P.D., and Gieseler, K. (2013) Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy. Hum. Mol. Genet.. 22(22):4562-78
Djiotsa, J., Verbruggen, V., Giacomotto, J., Ishibashi, M., Manning, E., Rinkwitz, S., Manfroid, I., Lvoz, M., and Peers, B. (2012) Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Developmental Biology. 12(1):37
Giacomotto, J., and Ségalat, L. (2010) High-throughput screening and small animal models, where are we?. British journal of pharmacology. 160(2):204-216

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods.
Giacomotto J, Ségalat L, Carre-Pierrat M, Gieseler K.
Methods. 2011 Oct 21. [Epub ahead of print]

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy.
Giacomotto, J; Pertl, C; Borrel, C, et al.
HUMAN MOLECULAR GENETICS Volume: 18 Issue: 21 Pages: 4089-4101 Published: 2009

Metabolic Profiling Strategy of Caenorhabditis elegans by Whole-Organism Nuclear Magnetic Resonance
Blaise*, BJ; Giacomotto*, J; Triba*, MN, et al.
JOURNAL OF PROTEOME RESEARCH Volume: 8 Issue: 5 Pages: 2542-2550 Published: 2009

Metabotyping of Caenorhabditis elegans reveals latent phenotypes
Blaise, BJ; Giacomotto, J; Elena, B, et al.
PNAS Volume: 104 Issue: 50 Pages: 19808-19812 Published: 2007

Blocking of striated muscle degeneration by serotonin in C. elegans
Carre-Pierrat, M; Mariol, MC; Chambonnier, L, et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY Volume: 27 Issue: 3-4 Pages: 253-258 Published: MAR 2006