ZFIN ID: ZDB-LAB-970507-36
Neurobiologie et Neuropharmacologie du Developpement
PI/Director: Legendre, Pascal
Contact Person: Legendre, Pascal
Email: pascal.legendre@snv.jussieu.fr
URL:
Address: IDN CNRS U1488 Neurobiologie et Neurpharmacologie du developpement Universite Pierre et Marie Curie Bat B, 6eme etage 7 quai St Bernard cedex 05 Paris, 75252 France
Country: France
Phone: 33-1-4427-2519
Fax: 33-1-4427-2781
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
Electrophysiological analysis of the developement of the inihibitory synaptic activity and related glycine channels in zebrafish hindbrain and spinal cord.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Zaupa, M., Naini, S.M.A., Younes, M.A., Bullier, E., Duboué, E.R., Le Corronc, H., Soula, H., Wolf, S., Candelier, R., Legendre, P., Halpern, M.E., Mangin, J.M., Hong, E. (2021) Trans-inhibition of axon terminals underlies competition in the habenulo-interpeduncular pathway. Current biology : CB. 31(21):4762-4772.e5
Rima, M., Lattouf, Y, Abi Younes, M., Bullier, E., Legendre, P., Mangin, J.M., Hong, E. (2020) Dynamic regulation of the cholinergic system in the spinal central nervous system. Scientific Reports. 10(1):15338
Pilorge, M., Fassier, C., Le Corronc, H., Potey, A., Bai, J., De Gois, S., Delaby, E., Assouline, B., Guinchat, V., Devillard, F., Delorme, R., Nygren, G., Råstam, M., Meier, J.C., Otani, S., Cheval, H., James, V.M., Topf, M., Dear, T.N., Gillberg, C., Leboyer, M., Giros, B., Gautron, S., Hazan, J., Harvey, R.J., Legendre, P., Betancur, C. (2016) Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Molecular psychiatry. 21(7):936-45
Rigo, J.M., and Legendre, P. (2006) Frequency-dependent modulation of glycine receptor activation recorded from the zebrafish larvae hindbrain. Neuroscience. 140(2):389-402
Rigo, J.M., Badiu, C., and Legendre, P. (2003) Heterogeneity of postsynaptic receptor occupancy fluctuations among glycinergic inhibitory synapses in the zebrafish hindbrain. The Journal of physiology. 553(3):819-832
Drapeau, P., Buss, R.R., Ali, D.W., Legendre, P., and Rotundo, R.L. (2001) Limits to the development of fast neuromuscular transmission in zebrafish. Journal of neurophysiology. 86(6):2951-2956
Suwa, H., Saint-Amant, L., Triller, A., Drapeau, P., and Legendre, P. (2001) High-affinity zinc potentiation of inhibitory postsynaptic glycinergic currents in the zebrafish hindbrain. Journal of neurophysiology. 85(2):912-925
Drapeau, P. and Legendre, P. (2001) Neuromuscular transmission on the rebound. Receptors & channels. 7(6):491-496
Ali, D.W., Drapeau, P., and Legendre, P. (2000) Development of spontaneous glycinergic currents in the mauthner neuron of the zebrafish embryo. Journal of neurophysiology. 84(4):1726-1736
Legendre P., Ali, D.W., and Drapeau, P. (2000) Recovery from open channel block by acetylcholine during neuromuscular transmission in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(1):140-148
Legendre, P. (1999) Voltage dependence of the glycine receptor-channel kinetics in the zebrafish hindbrain. Journal of neurophysiology. 82(5):2120-2129
Legendre, P. (1998) A reluctant gating mode of glycine receptor channels determines the time course of inhibitory miniature synaptic events in zebrafish hindbrain neuron. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18:2856-2870
Triller, A., Rostaing, P., Korn, H., and Legendre, P. (1997) Morphofunctional evidence for mature synaptic contacts on the Mauthner cell of 52-hour-old zebrafish larvae. Neuroscience. 80(1):133-145
Legendre, P. (1997) Pharmacological evidence for two types of postsynaptic glycinergic receptors on the Mauthner cell of 52-h-old zebrafish larvae. Journal of neurophysiology. 77(5):2400-2415
Legendre, P. and Korn, H. (1995) Voltage dependence of conductance changes evoked by glycine release in the zebrafish brain. Journal of neurophysiology. 73:2404-2412
Legendre, P. and Korn, H. (1994) Glycinergic inhibitory synaptic currents and related receptor channels in the zebrafish brain. The European journal of neuroscience. 6:1544-1557