ZFIN ID: ZDB-PERS-960805-324
Legendre, Pascal
Email: pascal.legendre@snv.jussieu.fr
Affiliation: Neurobiologie et Neuropharmacologie du Developpement
Address: Universite Pierre et Marie Curie Bât B, étage 6, boite postale 37 7 quai Saint Bernard Paris, 75252 France
Country: France
Phone: 33-1-4427-2519
Fax: 33-1-4427-2781

I am currently working on the inhibitory synaptic activity in the hindbrain of zebrafish larva using patch clamp recording techniques.

Pilorge, M., Fassier, C., Le Corronc, H., Potey, A., Bai, J., De Gois, S., Delaby, E., Assouline, B., Guinchat, V., Devillard, F., Delorme, R., Nygren, G., Råstam, M., Meier, J.C., Otani, S., Cheval, H., James, V.M., Topf, M., Dear, T.N., Gillberg, C., Leboyer, M., Giros, B., Gautron, S., Hazan, J., Harvey, R.J., Legendre, P., Betancur, C. (2016) Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Molecular psychiatry. 21(7):936-45
Rigo, J.M., and Legendre, P. (2006) Frequency-dependent modulation of glycine receptor activation recorded from the zebrafish larvae hindbrain. Neuroscience. 140(2):389-402
Rigo, J.M., Badiu, C., and Legendre, P. (2003) Heterogeneity of postsynaptic receptor occupancy fluctuations among glycinergic inhibitory synapses in the zebrafish hindbrain. The Journal of physiology. 553(3):819-832
Drapeau, P., Buss, R.R., Ali, D.W., Legendre, P., and Rotundo, R.L. (2001) Limits to the development of fast neuromuscular transmission in zebrafish. Journal of neurophysiology. 86(6):2951-2956
Suwa, H., Saint-Amant, L., Triller, A., Drapeau, P., and Legendre, P. (2001) High-affinity zinc potentiation of inhibitory postsynaptic glycinergic currents in the zebrafish hindbrain. Journal of neurophysiology. 85(2):912-925
Drapeau, P. and Legendre, P. (2001) Neuromuscular transmission on the rebound. Receptors & channels. 7(6):491-496
Ali, D.W., Drapeau, P., and Legendre, P. (2000) Development of spontaneous glycinergic currents in the mauthner neuron of the zebrafish embryo. Journal of neurophysiology. 84(4):1726-1736
Legendre P., Ali, D.W., and Drapeau, P. (2000) Recovery from open channel block by acetylcholine during neuromuscular transmission in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(1):140-148
Legendre, P. (1999) Voltage dependence of the glycine receptor-channel kinetics in the zebrafish hindbrain. Journal of neurophysiology. 82(5):2120-2129
Legendre, P. (1998) A reluctant gating mode of glycine receptor channels determines the time course of inhibitory miniature synaptic events in zebrafish hindbrain neuron. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18:2856-2870
Triller, A., Rostaing, P., Korn, H., and Legendre, P. (1997) Morphofunctional evidence for mature synaptic contacts on the Mauthner cell of 52-hour-old zebrafish larvae. Neuroscience. 80(1):133-145
Legendre, P. (1997) Pharmacological evidence for two types of postsynaptic glycinergic receptors on the Mauthner cell of 52-h-old zebrafish larvae. Journal of neurophysiology. 77(5):2400-2415
Legendre, P. and Korn, H. (1995) Voltage dependence of conductance changes evoked by glycine release in the zebrafish brain. Journal of neurophysiology. 73:2404-2412
Legendre, P. and Korn, H. (1994) Glycinergic inhibitory synaptic currents and related receptor channels in the zebrafish brain. The European journal of neuroscience. 6:1544-1557