ZFIN ID: ZDB-LAB-170214-20
Bing Hu Lab
PI/Director: Hu, Bing
Contact Person: Hu, Bing
Email: bhu@ustc.edu.cn
URL: http://zebrafish.ustc.edu.cn
Address: Lab of Neurodevelopment and Repair School of Life Sciences, CAS Key Laboratory of Brain Funtion and Desease, University of Science and Technology of China
Country: China
Phone: 137-2111-7805
Fax: +86-551-63601443
Line Designation: ah


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 3 genomic features


STATEMENT OF RESEARCH INTERESTS
1) To study the oligodendrocyte development, myelin formation as well as remyelination after injury. Currently, we are focusing on elucidation of the mechanisms underlying zebrafish CNS remyelination after injury.
2) To study the synapse dynamic change using in vivo time-lapse confocal microscopy imaging in zebrafish and xenopus tadpoles.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Shi, L., Wang, Z., Li, Y., Song, Z., Yin, W., Hu, B. (2023) Deletion of the chd7 Hinders Oligodendrocyte Progenitor Cell Development and Myelination in Zebrafish. International Journal of Molecular Sciences. 24(17):
Xu, H.D., Cheng, X., Sun, X., Chen, P., Zhan, W., Liu, X., Wang, X., Hu, B., Liang, G. (2023) Caspase-3-Triggered Intracellular Gadolinium Nanoparticle Formation for T1-Weighted Magnetic Resonance Imaging of Apoptosis In Vivo. Nano Letters. 23(13):6178-6183
Shao, G.J., Wang, X.L., Wei, M.L., Ren, D.L., Hu, B. (2023) DUSP2 deletion with CRISPR/Cas9 promotes Mauthner cell axonal regeneration at the early stage of zebrafish. Neural regeneration research. 18:577-581
Wang, Z., Wang, X., Shi, L., Cai, Y., Hu, B. (2022) Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway. Acta neuropathologica communications. 10:184184
Wang, J., Zheng, F., Yin, L., Shi, S., Hu, B., Qu, H., Zheng, L. (2022) Dopamine Level Affects Social Interaction and Color Preference Possibly Through Intestinal Microbiota in Zebrafish. Zebrafish. 19:81-93
Yang, L.Q., Chen, M., Ren, D.L., Hu, B. (2020) Dual Oxidase Mutant Retards Mauthner-Cell Axon Regeneration at an Early Stage via Modulating Mitochondrial Dynamics in Zebrafish. Neuroscience Bulletin. 36(12):1500-1512
Ge, S., Li, J., Huang, D., Cai, Y., Fang, J., Jiang, H., Hu, B. (2019) Strong static magnetic field delayed the early development of zebrafish. Open Biology. 9:190137
Wang, F., Ren, D., Liang, X., Ke, S., Zhang, B., Hu, B., Song, X., Wang, X. (2019) A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Nucleic acids research. 47(12):6315-6329
Chen, M., Huang, R.C., Yang, L.Q., Ren, D.L., Hu, B. (2019) In vivo imaging of evoked calcium responses indicates the intrinsic axonal regenerative capacity of zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(6):7721-7733
Shi, Q., Wang, Z., Chen, L., Fu, J., Han, J., Hu, B., Zhou, B. (2019) Optical toxicity of triphenyl phosphate in zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 210:139-147
Yang, L.Q., Chen, M., Zhang, J.L., Ren, D.L., Hu, B. (2018) Hypoxia Delays Oligodendrocyte Progenitor Cell Migration and Myelin Formation by Suppressing Bmp2b Signaling in Larval Zebrafish. Frontiers in Cellular Neuroscience. 12:348
Ren, D.L., Wang, X.B., Hu, B. (2018) Circadian gene period1b regulates proinflammatory cytokine expression through NF-κB signalling in zebrafish. Fish & shellfish immunology. 80:528-533
Li, Y., Huang, Y., Cao, X., Yin, X., Jin, X., Liu, S., Jiang, J., Jiang, W., Xiao, T.S., Zhou, R., Cai, G., Hu, B., Jin, T. (2018) Functional and Structural Characterization of Zebrafish ASC. The FEBS journal. 285(14):2691-2707
Ren, D.L., Zhang, J.L., Yang, L.Q., Wang, X.B., Wang, Z.Y., Huang, D.F., Tian, C., Hu, B. (2018) Circadian genes period1b and period2 differentially regulate inflammatory responses in zebrafish. Fish & shellfish immunology. 77:139-146
Huang, D.F., Wang, M.Y., Yin, W., Ma, Y.Q., Wang, H., Xue, T., Ren, D.L., Hu, B. (2018) Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency.. Frontiers in behavioral neuroscience. 12:53
Chen, L.L., Xie, J., Cao, D.D., Jia, N., Li, Y.J., Sun, H., Li, W.F., Hu, B., Chen, Y., Zhou, C.Z. (2018) The pore-forming protein Aep1 is an innate immune molecule that prevents zebrafish from bacterial infection. Developmental and comparative immunology. 82:49-54
Huang, R., Chen, M., Yang, L., Wagle, M., Guo, S., Hu, B. (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo.. Frontiers in molecular neuroscience. 10:375
Nie, K., Wang, K., Huang, D.F., Huang, Y.B., Yin, W., Ren, D.L., Wang, H., Hu, B. (2017) Effects of circadian clock protein Per1b on zebrafish visual functions. Chronobiology International. 35(2):160-168
Ren, D.L., Ji, C., Wang, X.B., Wang, H., Hu, B. (2017) Endogenous melatonin promotes rhythmic recruitment of neutrophils toward an injury in zebrafish. Scientific Reports. 7:4696
Xu, Y., Chen, M., Hu, B., Huang, R., Hu, B. (2017) In vivo Imaging of Mitochondrial Transport in Single-Axon Regeneration of Zebrafish Mauthner Cells.. Frontiers in Cellular Neuroscience. 11:4
Chen, M., Xu, Y., Huang, R., Huang, Y., Ge, S., Hu, B. (2016) N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular neurobiology. 54(9):6917-6930
Ren, D.L., Sun, A.A., Li, Y.J., Chen, M., Ge, S.C., Hu, B. (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. The Journal of endocrinology. 227(1):49-60