Person
Hu, Bing
|
Biography and Research Interest
Hu Bing, professor and Ph.D. supervisor at USTC, is selected into CAS Hundred Talents Program. He graduated from USTC and obtained Bachelor Degree of Biophysics in 1989, Master Degree of Biophysics in 1992 and Doctoral Degree from Shanghai Institute of Physiology of Chinese Academy of Sciences in 1999 (jointly trained by Shanghai Institute of Physiology of Chinese Academy of Sciences and Medical Faculty of the University of Hong Kong). In 2001 he served as postdoctoral fellow at Department of Anatomy, Medical Faculty of the University of Hong Kong; from January 2002 to November 2004 he served as postdoctoral fellow at University of California, Los Angeles & Irvine). In 2007, before he was selected into CAS Hundred Talents Program, he served as Research Officer at Department of Anatomy, Medical Faculty of the University of Hong Kong. Over the years he has studied Developmental Neurobiology and the repair mechanisms underlying neural damage and published 30 academic papers in SCI journals. His papers have been cited by others more than 1000 times. He once made detailed research on localization and function of p75 and Trks neurotrophin receptors in the retina of the adult SD rat (published in Glia, 1998), BDNF increases synapse density in dendrites of developing tectal neurons in vivo (published in Development, 2005-2006) and LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis (published in Nature Medicine, 2007). In the autumn of 2007 he established an independent research laboratory at USTC, and conducted mechanism research of nerve growth, synapses development and damage repair in model animals-xenopus and zebrafish with bioluminescence in-vivo imaging technology. In 1997 he won the Second Prize of Natural Sciences Award of Chinese Academy Sciences and Best Research Output Award of University of Hong Kong for the year 2007-2008. In 2009 he won the third prize of the Third PharmaTech Life and Chemistry Research Award.
Non-Zebrafish Publications
Xu Y, Chen M, Hu B, Huang R and Hu B* (2017) In vivo Imaging of Mitochondrial Transport in Single-Axon Regeneration of Zebrafish Mauthner Cells. Front. Cell. Neurosci. 11:4. doi: 10.3389/fncel.2017.00004
Chen, M., Xu, Y., Huang, R., Huang Yubin, Ge Shuchao and Hu Bing(2016) N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular Neurobiology, (), 1-14. doi:10.1007/s12035-016-0233-4
Tian C, Zou S, Hu B*(2016) Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2129-38. doi: 10.1167/iovs.15-17675. (highlight in the same issue)
Da-Long Ren, Ai-Ai Sun, Ya-Juan Li, Min Chen, Shu-Chao Ge and Bing Hu* (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. Journal of Endocrinology. 227(1) :49–60. DOI: 10.1530/JOE-15-0329. Epub 2015 Aug 24. (cover page)
Da-long Ren1, Ya-juan Li1, Bing-bing Hu1, Han Wang* 2, 3 and Bing Hu*1 (2015)Melatonin regulates the rhythmic migration of neutrophils in live zebrafish. J Pineal Res., 2015 May;58(4):452-60. doi: 10.1111/jpi.12230. Epub 2015 Mar 26.
Yue Yuan,?,^ Hongbin Sun,?,^ Shuchao Ge,§,^ Mengjing Wang,? Hongxin Zhao,? Lin Wang,§ Linna An,? Jia Zhang,? Huafeng Zhang,§ Bing Hu,*,§ Junfeng Wang,*,? and Gaolin Liang*,? (2015)Controlled Intracellular Self-Assembly and Disassembly of 19F Nanoparticles for MR Imaging of Caspase 3/7 in Zebrafish. ACS nano. Jan 27; 9(1):761-8. doi: 10.1021/nn5062657. Epub 2014 Dec 30.
Yin, W., Hu, B*. (2014) Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp. Neurol. 251:72-83.
Meng-Hua Xiong,?,? Ya-Juan Li,§,? Yan Bao,§ Xian-Zhu Yang,§ Bing Hu*,§ and Jun Wang*,§ (2012) Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery. Advanced Materials. 24, 6175–6180.
Sha Mi*, Bing Hu*, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu* (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Medicine. 13(10):1228-1233.
Bing Hu, Angeliki Maria Nikolakopoulou and Susana Cohen-Cory (2005) BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo. Development. 132:4285-4298.
Bing Hu, Henry K. Yip and Kwok-Fai So (1998) Localization of p75 neurotrophin receptor in the retina of the adult SD rat: An immunocytochemical study at light and electron microscopic levels. Glia 24:187-197.