ZFIN ID: ZDB-LAB-130430-1
Lingfei Luo Lab
PI/Director: Luo, Lingfei
Contact Person: Luo, Lingfei
Email: lluo@swu.edu.cn
Address: School of Life Sciences, Southwest University 2 Tiansheng Road, Beibei 400715 Chongqing China
Country: China
Phone: +86-23-68367957
Fax: +86-23-68367958
Line Designation: cq

Show first 50 of 75 genomic features

Development and regeneration of digestive organs in particular liver and pancreas.

Ma, Jun Post-Doc He, Jianbo Graduate Student Lu, Huiqiang Graduate Student
Shi, Wenchao Graduate Student Yang, Yun Graduate Student Zou, Qingliang Graduate Student
Tang, Xuemei Technical Staff

Bao, W., Wang, X., Luo, L., Ni, R. (2021) The Lysosomal Storage Disorder Due to fig4a Mutation Causes Robust Liver Vacuolation in Zebrafish. Zebrafish. 18(3):175-183
Zhang, W., Chen, J., Ni, R., Yang, Q., Luo, L., He, J. (2021) Contributions of biliary epithelial cells to hepatocyte homeostasis and regeneration in zebrafish. iScience. 24:102142
Ma, J., Huang, Y., Peng, Y., Xu, Z., Wang, Z., Chen, X., Xie, S., Jiang, P., Zhong, K., Lu, H. (2021) Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 274:116539
Cao, Z., Meng, Y., Gong, F., Xu, Z., Liu, F., Fang, M., Zou, L., Liao, X., Wang, X., Luo, L., Li, X., Lu, H. (2021) Calcineurin controls proximodistal blastema polarity in zebrafish fin regeneration. Proceedings of the National Academy of Sciences of the United States of America. 118(2):
Peng, Y., Li, M., Huang, Y., Cheng, B., Cao, Z., Liao, X., Xiong, G., Liu, F., Hu, C., Lu, H. (2021) Bifenazate induces developmental and immunotoxicity in zebrafish. Chemosphere. 271:129457
Cheng, B., Zou, L., Zhang, H., Cao, Z., Liao, X., Shen, T., Xiong, G., Xiao, J., Liu, H., Lu, H. (2021) Effects of cyhalofop-butyl on the developmental toxicity and immunotoxicity in zebrafish (Danio rerio). Chemosphere. 263:127849
He, J., Mo, D., Chen, J., Luo, L. (2020) Combined whole-mount fluorescence in situ hybridization and antibody staining in zebrafish embryos and larvae. Nature Protocols. 15:3361-3379
Huang, Y., Chen, Z., Meng, Y., Wei, Y., Xu, Z., Ma, J., Zhong, K., Cao, Z., Liao, X., Lu, H. (2020) Famoxadone-cymoxanil induced cardiotoxicity in zebrafish embryos. Ecotoxicology and environmental safety. 205:111339
Xu, Z., Ni, H., Huang, Y., Meng, Y., Cao, Z., Liao, X., Zhang, S., Guo, X., Lu, H. (2020) Effect of fomesafen on the embryonic development of zebrafish. Chemosphere. 259:127380
Hu, L., Li, H., Chi, Z., He, J. (2020) Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish. The Journal of biological chemistry. 295(33):11466-11472
Sun, X., Zhang, R., Chen, H., Du, X., Chen, S., Huang, J., Liu, M., Xu, M., Luo, F., Jin, M., Su, N., Qi, H., Yang, J., Tan, Q., Zhang, D., Ni, Z., Liang, S., Zhang, B., Chen, D., Zhang, X., Luo, L., Chen, L., Xie, Y. (2020) Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling. Theranostics. 10:7111-7130
Cheng, B., Jiang, F., Su, M., Zhou, L., Zhang, H., Cao, Z., Liao, X., Xiong, G., Xiao, J., Liu, F., Lu, H. (2020) Effects of lincomycin hydrochloride on the neurotoxicity of zebrafish. Ecotoxicology and environmental safety. 201:110725
Huang, Y., Ma, J., Meng, Y., Wei, Y., Xie, S., Jiang, P., Wang, Z., Chen, X., Liu, Z., Zhong, K., Cao, Z., Liao, X., Xiao, J., Lu, H. (2020) Exposure to Oxadiazon-Butachlor causes cardiac toxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 265:114775
Zhang, J., Deng, Y., Cheng, B., Huang, Y., Meng, Y., Zhong, K., Xiong, G., Guo, J., Liu, Y., Lu, H. (2020) Protective effects and molecular mechanisms of baicalein on thioacetamide-induced toxicity in zebrafish larvae. Chemosphere. 256:127038
Meng, Y., Zhong, K., Xiao, J., Huang, Y., Wei, Y., Tang, L., Chen, S., Wu, J., Ma, J., Cao, Z., Liao, X., Lu, H. (2020) Exposure to pyrimethanil induces developmental toxicity and cardiotoxicity in zebrafish. Chemosphere. 255:126889
Xiong, G., Deng, Y., Liao, X., Zhang, J., Cheng, B., Cao, Z., Lu, H. (2020) Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (Danio rerio). Nanotoxicology. 14(5):667-682
Sun, X., Zhou, Y., Zhang, R., Wang, Z., Xu, M., Zhang, D., Huang, J., Luo, F., Li, F., Ni, Z., Zhou, S., Chen, H., Chen, S., Chen, L., Du, X., Chen, B., Huang, H., Liu, P., Yin, L., Qiu, J., Chen, D., Deng, C., Xie, Y., Luo, L., Chen, L. (2020) Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway. Nature communications. 11:479
Jia, K., Cheng, B., Huang, L., Xiao, J., Bai, Z., Liao, X., Cao, Z., Shen, T., Zhang, C., Hu, C., Lu, H. (2020) Thiophanate-methyl induces severe hepatotoxicity in zebrafish. Chemosphere. 248:125941
Cao, Z., Huang, Y., Xiao, J., Cao, H., Peng, Y., Chen, Z., Liu, F., Wang, H., Liao, X., Lu, H. (2020) Exposure to diclofop-methyl induces cardiac developmental toxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 259:113926
Cheng, B., Zhang, H., Hu, J., Peng, Y., Yang, J., Liao, X., Liu, F., Guo, J., Hu, C., Lu, H. (2020) The immunotoxicity and neurobehavioral toxicity of zebrafish induced by famoxadone-cymoxanil. Chemosphere. 247:125870
Huang, S., Wang, Y., Luo, L., Li, X., Jin, X., Li, S., Yu, X., Yang, M., Guo, Z. (2019) BMP2 Is Related to Hirschsprung's Disease and Required for Enteric Nervous System Development. Frontiers in Cellular Neuroscience. 13:523
Cheng, B., Zhang, H., Jia, K., Li, E., Zhang, S., Yu, H., Cao, Z., Xiong, G., Hu, C., Lu, H. (2019) Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. Fish & shellfish immunology. 96:114-121
Dong, G., Huang, Y., Ding, H., Luo, L., Zhang, Y., Huang, H., Ruan, H. (2019) Mypt1 regulates Bmp signaling to promote embryonic exocrine pancreas growth in zebrafish. Genesis (New York, N.Y. : 2000). 58(2):e23345
Xiong, G., Deng, Y., Cao, Z., Liao, X., Zhang, J., Lu, H. (2019) The hepatoprotective effects of Salvia plebeia R. Br. extract in zebrafish (Danio rerio). Fish & shellfish immunology. 95:399-410
Wang, H., Zhou, L., Meng, Z., Su, M., Zhang, S., Huang, P., Jiang, F., Liao, X., Cao, Z., Lu, H. (2019) Clethodim exposure induced development toxicity and behaviour alteration in early stages of zebrafish life. Environmental pollution (Barking, Essex : 1987). 255:113218
Huang, Y., Lu, Y., He, Y., Feng, Z., Zhan, Y., Huang, X., Liu, Q., Zhang, J., Li, H., Huang, H., Ma, M., Luo, L., Li, L. (2019) Ikzf1 regulates embryonic T lymphopoiesis via Ccr9 & Irf4 in zebrafish. The Journal of biological chemistry. 294(44):16152-16163
Xiong, G., Deng, Y., Li, J., Cao, Z., Liao, X., Liu, Y., Lu, H. (2019) Immunotoxicity and transcriptome analysis of zebrafish embryos in response to glufosinate-ammonium exposure. Chemosphere. 236:124423
Cao, Z., Zou, L., Wang, H., Zhang, H., Liao, X., Xiao, J., Zhang, S., Lu, H. (2019) Exposure to diclofop-methyl induces immunotoxicity and behavioral abnormalities in zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 214:105253
Chen, J., Yu, T., He, X., Fu, Y., Dai, L., Wang, B., Wu, Y., He, J., Li, Y., Zhang, F., Zhao, J., Liu, C. (2019) Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration. Biochemical and Biophysical Research Communications. 516(3):680-685
Meng, Y., Ma, J., Lin, T., Jiang, H., Wang, C., Yang, F., Zhou, X. (2019) Functional variants of hepatocyte growth factor identified in patients with adolescent idiopathic scoliosis. Journal of cellular biochemistry. 120(10):18236-18245
He, J., Chen, J., Wei, X., Leng, H., Mu, H., Cai, P., Luo, L. (2019) mTORC1 Signaling is Required for the Dedifferentiation from Biliary Cell to Bi-potential Progenitor Cell in Zebrafish Liver Regeneration. Hepatology (Baltimore, Md.). 70(6):2092-2106
Qiu, L., Jia, K., Huang, L., Liao, X., Guo, X., Lu, H. (2019) Hepatotoxicity of tricyclazole in zebrafish (Danio rerio). Chemosphere. 232:171-179
Chen, J., He, J., Ni, R., Yang, Q., Zhang, Y., Luo, L. (2019) Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish. Developmental Cell. 49(5):697-710.e5
Wang, H., Meng, Z., Zhou, L., Cao, Z., Liao, X., Ye, R., Lu, H. (2019) Effects of acetochlor on neurogenesis and behaviour in zebrafish at early developmental stages. Chemosphere. 220:954-964
Wang, H., Zhou, L., Liao, X., Meng, Z., Xiao, J., Li, F., Zhang, S., Cao, Z., Lu, H. (2019) Toxic effects of oxine-copper on development and behavior in the embryo-larval stages of zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 210:242-250
Cao, Z., Mao, X., Luo, L. (2019) Germline Stem Cells Drive Ovary Regeneration in Zebrafish. Cell Reports. 26:1709-1717.e3
Yi, X., Yu, J., Ma, C., Dong, G., Shi, W., Li, H., Li, L., Luo, L., Sampath, K., Ruan, H., Huang, H. (2019) The effector of Hippo signaling, Taz, is required for formation of the micropyle and fertilization in zebrafish. PLoS Genetics. 15:e1007408
Zhong, Y., Huang, W., Du, J., Wang, Z., He, J., Luo, L. (2018) Improved Tol2-mediated enhancer trap identifies weakly expressed genes during liver and β cell development and regeneration in zebrafish. The Journal of biological chemistry. 294(3):932-940
Gao, C., Huang, W., Gao, Y., Jan Lo, L., Luo, L., Huang, H., Chen, J., Peng, J. (2018) Zebrafish hhex-null mutant develops an intrahepatic intestinal tube due to de-repression of cdx1b and pdx1. Journal of molecular cell biology. 11(6):448-462
Wang, Z., Song, J., Luo, L., Ma, J. (2018) Loss of Leucyl-tRNA synthetase b leads to ILFS1-like symptoms in zebrafish. Biochemical and Biophysical Research Communications. 505(2):378-384
Zhan, Y., Huang, Y., Chen, J., Cao, Z., He, J., Zhang, J., Huang, H., Ruan, H., Luo, L., Li, L. (2018) The caudal dorsal artery generates hematopoietic stem and progenitor cells via the endothelial-to-hematopoietic transition in zebrafish. Journal of genetics and genomics = Yi chuan xue bao.
Zou, Q., Gang, K., Yang, Q., Liu, X., Tang, X., Lu, H., He, J., Luo, L. (2018) The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish. The Journal of biological chemistry. 293(31):11971-11983
Yi, X., Yu, J., Ma, C., Li, L., Luo, L., Li, H., Ruan, H., Huang, H. (2018) Yap1/Taz are essential for the liver development in zebrafish. Biochemical and Biophysical Research Communications. 503(1):131-137
Ni, R., Luo, L. (2018) A noncanonical function of histidyl-tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development. FEBS Open Bio. 8:722-731
Gao, C., Zhu, Z., Gao, Y., Lo, L.J., Chen, J., Luo, L., Peng, J. (2018) Hepatocytes in a normal adult liver are derived solely from the embryonic hepatocytes. Journal of genetics and genomics = Yi chuan xue bao. 45:173-175
Cai, P., Mao, X., Zhao, J., Luo, L. (2018) Ribosome biogenesis protein Urb2 regulates hematopoietic stem cells development via P53 pathway in zebrafish. Biochemical and Biophysical Research Communications. 497(2):776-782
He, J., Yang, Y., Zhang, J., Chen, J., Wei, X., He, J., Luo, L. (2017) Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 44(12):567-576
Tian, Y., Xu, J., Feng, S., He, S., Zhao, S., Zhu, L., Jin, W., Dai, Y., Luo, L., Qu, J.Y., Wen, Z. (2017) The first wave of T lymphopoiesis in zebrafish arises from aorta endothelium independent of hematopoietic stem cells. The Journal of experimental medicine. 214(11):3347-3360
Zhao, F., Shi, Y., Huang, Y., Zhan, Y., Zhou, L., Li, Y., Wan, Y., Li, H., Huang, H., Ruan, H., Luo, L., Li, L. (2017) Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 32(1):149-158
Wang, H., Luo, L., Yang, D. (2017) Loss of Gspt1l disturbs the patterning of the brain central arteries in zebrafish. Biochemical and Biophysical Research Communications. 486(1):156-162
Du, J., Yang, Q., Luo, L., Yang, D. (2017) C1qr and C1qrl redundantly regulate angiogenesis in zebrafish through controlling endothelial Cdh5. Biochemical and Biophysical Research Communications. 483(1):482-487
Hou, Y., Sheng, Z., Mao, X., Li, C., Chen, J., Zhang, J., Huang, H., Ruan, H., Luo, L., Li, L. (2016) Systemic inoculation of Escherichia coli causes emergency myelopoiesis in zebrafish larval caudal hematopoietic tissue. Scientific Reports. 6:36853
Chen, J., He, J., Li, L., Yang, D., Luo, L. (2016) Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Scientific Reports. 6:26608
Liu, C., Wu, C., Yang, Q., Gao, J., Li, L., Yang, D., Luo, L. (2016) Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction. Immunity. 44(5):1162-76
Cao, Z., Wang, H., Mao, X., Luo, L. (2016) Noncanonical function of Threonyl-tRNA synthetase regulates Vascular Development in Zebrafish. Biochemical and Biophysical Research Communications. 473(1):67-72
Zhao, C., Zhang, W., Zhao, Y., Yang, Y., Luo, H., Ji, G., Dong, E., Deng, H., Lin, S., Wei, Y., Yang, H. (2016) Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism. Scientific Reports. 6:19404
Jia, X.E., Ma, K., Xu, T., Gao, L., Wu, S., Fu, C., Zhang, W., Wang, Z., Liu, K., Dong, M., Jing, C., Ren, C., Dong, Z., Chen, Y., Jin, Y., Huang, Q., Chang, X., Deng, M., Li, L., Luo, L., Zhu, J., Dang, Y., Chang, H.C., Zon, L.I., Zhou, Y., Chen, S., Pan, W. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. 25(8):946-62
Jiang, F., Chen, J., Ma, X., Huang, C., Zhu, S., Wang, F., Li, L., Luo, L., Ruan, H., Huang, H. (2015) Analysis of mutants from a genetic screening reveals the control of intestine and liver development by many common genes in zebrafish. Biochemical and Biophysical Research Communications. 460(3):838-44
Shi, W., Fang, Z., Li, L., Luo, L. (2015) Using zebrafish as the model organism to understand organ regeneration. Science China. Life sciences. 58:343-51
Yan, Q., Zhang, Q., Yang, H., Zou, Q., Tang, C., Fan, N., Lai, L. (2014) Generation of multi-gene knockout rabbits using the Cas9/gRNA system. Cell regeneration (London, England). 3:12
Shi, Y., Zhang, Y., Zhao, F., Ruan, H., Huang, H., Luo, L., Li, L. (2014) Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish. Scientific Reports. 4:5602
He, J., Lu, H., Zou, Q., and Luo, L. (2014) Regeneration of Liver After Extreme Hepatocyte Loss Occurs Mainly via Biliary Transdifferentiation in Zebrafish. Gastroenterology. 146(3):789-800.e8
Parker, M.O., Ife, D., Ma, J., Pancholi, M., Smeraldi, F., Straw, C., and Brennan, C.H. (2013) Development and automation of a test of impulse control in zebrafish. Frontiers in Systems Neuroscience. 7:65
Li, L., and Luo, L.F. (2013) Zebrafish as the model system to study organogenesis and regeneration. Yi chuan = Hereditas. 35(4):421-432
Lu, H., Ma, J., Yang, Y., Shi, W., and Luo, L. (2013) EpCAM Is an Endoderm-Specific Wnt Derepressor that Licenses Hepatic Development. Developmental Cell. 24(5):543-553
Huang, S., Ma, J., Liu, X., Zhang, Y., and Luo, L. (2011) Retinoic acid signaling sequentially controls visceral and heart laterality in Zebrafish. The Journal of biological chemistry. 286(32):28533-43
Huang, S., Ma, J., Liu, X., Zhang, Y., and Luo, L. (2011) Geminin is required for left-right patterning through regulating Kupffer's vesicle formation and ciliogenesis in zebrafish. Biochemical and Biophysical Research Communications. 410(2):164-9
Liu, X., Huang, S., Ma, J., Li, C., Zhang, Y., and Luo, L. (2009) NF-kappaB and Snail1a coordinate the cell cycle with gastrulation. The Journal of cell biology. 184(6):805-815