ZFIN Lab: Chatti Lab

ZFIN ID: ZDB-LAB-111121-1

ZFIN ID: ZDB-LAB-111121-1

Chatti Lab

PI/Director:	Chatti, Kiranam
Contact Person:	Chatti, Kiranam
Email:	kiranamc@drils.org
URL:	http://drils.org/team/kiranam-chatti/
Address:	Dept. of Biology, Dr. Reddy’s Institute of Life Sciences (DRILS), University of Hyderabad Campus Gachibowli, Hyderabad - 500046
Country:	India
Phone:	+91-40-66571532
Fax:	+91-40-66571581
Line Designation:	rdd

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 1 genomic features

STATEMENT OF RESEARCH INTERESTS

Tyrosine kinase biology and regulation in zebrafish, focusing on the BRK tyrosine kinase.
Non-catalytic splice variant of the BRK tyrosine kinase and its regulation.

LAB MEMBERS

Irlapati, Vamsi Krishna Graduate Student

Sarvepalli, Tejasudha Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Medishetti, R., C, M.R., Chatti, K. (2023) Cabozantinib-induced edema in zebrafish represents an adverse effect characterized by defects in lymphatic vasculature and renal function. Journal of biochemical and molecular toxicology. 37(9):e23413

Balamurugan, K., Medishetti, R., Rao, P., K, R.V., Chatti, K., Parsa, K.V.L. (2022) Protocol to evaluate hyperlipidemia in zebrafish larvae. STAR protocols. 3:101819

Balamurugan, K., Medishetti, R., Kotha, J., Behera, P., Chandra, K., Mavuduru, V.A., Joshi, M.B., Samineni, R., Katika, M.R., Ball, W.B., Thondamal, M., Challa, A., Chatti, K., Parsa, K.V.L. (2022) PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways. iScience. 25:103766

Foster, S.D., Glover, S.R., Turner, A.N., Chatti, K., Challa, A.K. (2018) A mixing heteroduplex mobility assay (mHMA) to genotype homozygous mutants with small indels generated by CRISPR-Cas9 nucleases. MethodsX. 6:1-5

Vemula, M.H., Medisetti, R., Ganji, R., Jakkala, K., Sankati, S., Chatti, K., Banerjee, S. (2016) Mycobacterium tuberculosis Zinc Metalloprotease-1 Assists Mycobacterial Dissemination in Zebrafish. Frontiers in microbiology. 7:1347

Bhanushali, U., Rajendran, S., Sarma, K., Kulkarni, P., Chatti, K., Chatterjee, S., Ramaa, C.S. (2016) 5-Benzylidene-2,4-thiazolidenedione derivatives: Design, synthesis and evaluation as inhibitors of angiogenesis targeting VEGR-2. Bioorganic chemistry. 67:139-147

Kulkarni, P., Chaudhari, G.H., Sripuram, V., Banote, R.K., Kirla, K.T., Sultana, R., Rao, P., Oruganti, S., Chatti, K. (2014) Oral dosing in adult zebrafish: Proof-of-concept using pharmacokinetics and pharmacological evaluation of carbamazepine. Pharmacological reports : PR. 66:179-183

Babu, P.V., Mukherjee, S., Deora, G.S., Chennubhotla, K.S., Medisetti, R., Yellanki, S., Kulkarni, P., Sripelly, S., Parsa, K.V., Chatti, K., Mukkanti, K., and Pal, M. (2013) Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo. Organic & biomolecular chemistry. 11(39):6680-5

Challa, A.K., and Chatti, K. (2013) Conservation and Early Expression of Zebrafish Tyrosine Kinases Support the Utility of Zebrafish as a Model for Tyrosine Kinase Biology. Zebrafish. 10(3):264-74

Dulla, B., Kirla, K.T., Rathore, V., Deora, G.S., Kavela, S., Maddika, S., Chatti, K., Reiser, O., Iqbal, J., and Pal, M. (2013) Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties. Organic & biomolecular chemistry. 11(19):3103-7

Banote, R.K., Koutarapu, S., Chennubhotla, K.S., Chatti, K., and Kulkarni, P. (2013) Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish. Epilepsy & behavior : E&B. 27(1):212-219

Chaudhari, G.H., Chennubhotla, K.S., Chatti, K., and Kulkarni, P. (2013) Optimization of the adult zebrafish ECG method for assessment of drug-induced QTc prolongation. Journal of Pharmacological and Toxicological Methods. 67(2):115-120

Reddy, E.R., Banote, R.K., Chatti, K., Kulkarni, P., and Rajadurai, M.S. (2012) Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles. Chembiochem : a European journal of chemical biology. 13(13):1889-1894

Rana, N., Moond, M., Marthi, A., Bapatla, S., Sarvepalli, T., Chatti, K., and Challa, A.K. (2010) Caffeine-induced effects on heart rate in zebrafish embryos and possible mechanisms of action: an effective system for experiments in chemical biology. Zebrafish. 7(1):69-81