Phenotype: | granulosa cell gata4 expression absent, abnormal |
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Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
Name: | granulosa cell |
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Synonyms: | granulosa cells |
Definition: | A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. |
Ontology: | Anatomy Ontology [ZFA:0009227] |
EXPRESSED GENE:
Symbol: | gata4 |
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Name: | GATA binding protein 4 |
Location: | Chr: 20 Mapping Details/Browsers |
EXPRESSION QUALITY:
Name: | absent |
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Synonyms: | absence, absent from organism |
Definition: | A quality denoting the lack of an entity. |
Ontology: | Phenotypic Quality Ontology [PATO:0000462] |