ZFIN ID: ZDB-GENE-980526-476
Gene Name: GATA binding protein 4
Gene Symbol: gata4
Sequence Ontology ID : SO:0000704

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Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity; involved in several  ...
GENE EXPRESSION
All Expression Data: 67 figures from 48 publications
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh320 Point Mutation Unknown Unknown ENU
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh321 Point Mutation Unknown Unknown ENU
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • gata4_unrecovered Point Mutation Unknown Unknown ENU
    sa44950 Point Mutation Unknown Unknown ENU
    sa45720 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 9 figures from 5 publications
    Observed in:
    DISEASE ASSOCIATED WITH gata4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    atrial heart septal defect 2 Atrial septal defect 2 607941
    atrioventricular septal defect Atrioventricular septal defect 4 614430
    tetralogy of Fallot Tetralogy of Fallot 187500
    ventricular septal defect Ventricular septal defect 1 614429
    ?Testicular anomalies with or without congenital heart disease 615542
    DISEASE ASSOCIATED WITH gata4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardioblast migration to the midline involved in heart field formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000679 (1)
  • InterPro:IPR008013 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR016375 (1)
  • InterPro:IPR039355 (1)
  • PROSITE:PS00344 (1)
  • PROSITE:PS50114 (1)
  • Pfam:PF00320 (1)
  • Pfam:PF05349 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gata4-201 (1) 1214
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gata4
    MARKER RELATIONSHIPS
    gata4Contained in: [BAC] CH73-107C13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131236 (1) 1173bp
    Genomic GenBank:CU207296 (1) 98771bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ILP3 (1) 352aa
    Sequence Clusters UniGene:81306 (1)
    Sequence Information (all 12)
    OTHER gata4 GENE PAGES
  • Alliance (1)
  • Gene:30483 (1)
  • VEGA:OTTDARG00000028850 (1)
  • Ensembl(GRCz11):ENSDARG00000098952 (1)
  • ORTHOLOGY for gata4 (Chr: 20)
    CITATIONS (133)