| Phenotype: | thymus trac expression decreased amount, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | thymus |
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| Synonyms: | |
| Definition: | Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion. |
| Ontology: | Anatomy Ontology [ZFA:0001078] |
EXPRESSED GENE:
| Symbol: | trac | ||||||||||||
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| Name: | T cell receptor alpha constant | ||||||||||||
| Previous Names: | TCRAC (1), 3745 (1), si:busm1-172d23.25, si:busm1-172d23.26, si:busm1-172d23.27, si:dz172d23.25, si:dz172d23.26, si:dz172d23.27, TCR1 (1), TCR8RC (1), TCRA3 (1) | ||||||||||||
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| Location: | Chr: 2 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |