12-hydroxynevirapine

Term ID

CHEBI:145206

Synonyms

11-cyclopropyl-4-(hydroxymethyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
12-hydroxy-nevirapine
12-hydroxy-NVP
12-OH-NVP
N(11)-cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one

(all 6)

Definition

A dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine.

References

(all 16)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic primary alcohol cyclopropanes dipyridodiazepine

aromatic primary alcohol cyclopropanes dipyridodiazepine Show first 5 Terms
has_functional_parent: nevirapine

nevirapine Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms

Phenotype

Phenotype resulting from 12-hydroxynevirapine

Phenotype where environments contain 12-hydroxynevirapine

Phenotype modified by environments containing 12-hydroxynevirapine

Phenotype affecting 12-hydroxynevirapine

Human Disease Model