nevirapine

Term ID

CHEBI:63613

Synonyms

• 11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
• 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
• NEV
• Nevirapine
• NVP
• Viramune

Definition

A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

References

• cas:129618-40-2
• drugbank:DB00238
• kegg.compound:C07263
• kegg.drug:D00435
• lincs.smallmolecule:LSM-5336
• pdb-ccd:NVP
• pubmed:1712395
• pubmed:25017682
• pubmed:28782122
• pubmed:28786740
• pubmed:28819312
• pubmed:28827836
• pubmed:28835669
• reaxys:4757598
• wikipedia.en:Nevirapine

Ontology

ChEBI  ( EBI )

Resources

CTD