OBO ID: CHEBI:167656

Term Name:	brivanib alaninate		Search Ontology:
Synonyms:	(1R,2S)-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-yl (2S)-2-aminopropanoate (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-yl L-alaninate alaninate de brivanib alaninati brivanibum alaninato de brivanib BMS 582664 BMS-582664 BMS582664 brivanib alaninate
Definition:	A carboxylic ester resulting from the formal condensation of the carboxy group of L-alanine with the hydroxy group of brivanib. It is a prodrug of brivanib (BMS-540215), a potent oral dual inhibitor of VEGFR-2 and FGFR-1 (IC50 of 25 nM and 148 nM, respectively) and was in development for the treatment of hepatocellular and colon carcinomas.
References:	CAS:649735-63-7 Chemspider:9330033 DrugBank:DB11865 KEGG:D08878 PMID:16570908 PMID:17638901 PMID:18288793 PMID:18815076 PMID:18829493 PMID:19396600 PMID:20024612 PMID:20303261 PMID:21115896 PMID:21289073 PMID:21391890 PMID:21629245 PMID:21659627 PMID:22189636 PMID:22983304 PMID:23030483 PMID:23690424 PMID:24325631 PMID:24780101 PMID:25470221 PMID:25724158 PMID:26852852 PMID:27771049 PMID:30855507 Wikipedia:Brivanib_alaninate
Ontology:	ChEBI  ( EBI )