ZFIN ChEBI: andrastin B

OBO ID: CHEBI:142862

Term Name:	andrastin B		Search Ontology:
Synonyms:	methyl (3beta,5beta,8alpha,9beta,10alpha,13alpha)-3-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxoandrosta-11,15-diene-14-carboxylate methyl 3beta-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxo-5beta,8alpha,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate
Definition:	A 17-oxo steroid that is andrastin C in which a hydrogen of the methyl group at position 19 has been replaced by a hydroxy group. A farnesyltransferase inhibitor produced by Penicillium roqueforti, a filamentous fungus involved in the ripening of several kinds of blue cheeses.
References:	PMID:15826038 PMID:8682716 PMID:8682717
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	5beta steroid 15-hydroxy steroid 17-oxo steroid 19-hydroxy steroid acetate ester ... Show All 9 Terms 5beta steroid 15-hydroxy steroid 17-oxo steroid 19-hydroxy steroid acetate ester enol meroterpenoid methyl ester primary alcohol Show first 5 Terms
has_functional_parent:	andrastin C andrastin C Show first 5 Terms
has_role:	EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite Show first 5 Terms
inverse has_functional_parent:	andrastin A andrastin A Show first 5 Terms
inverse is_conjugate_base_of:	andrastin B(1-) andrastin B(1-) Show first 5 Terms
is_conjugate_acid_of:	andrastin B(1-) andrastin B(1-) Show first 5 Terms

PHENOTYPE No data available