andrastin C

Term ID

CHEBI:142867

Synonyms

methyl (3beta,5beta,8alpha,9beta,10alpha,13alpha)-3-(acetyloxy)-15-hydroxy-4,4,8,12,16-pentamethyl-17-oxoandrosta-11,15-diene-14-carboxylate
methyl 3beta-(acetyloxy)-15-hydroxy-4,4,8alpha,12,16-pentamethyl-17-oxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate

Definition

A 17-oxosteroid that is 17-oxo-5beta,9beta,10alpha,13alpha-androsta-11,15-dieneandroxta-11,15-diene which is substituted by an acetoxy group at the 3beta position, methyl groups at the 4, 4, 8, 12, and 16 positions, a methoxycarbonyl group at position 14, and a hydroxy group at position 15. A farnesyltransferase inhibitor produced by Penicillium roqueforti, a filamentous fungus involved in the ripening of several kinds of blue cheeses.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 5beta steroid 15-hydroxy steroid 17-oxo steroid acetate ester enol ... Show All 7 Terms

5beta steroid 15-hydroxy steroid 17-oxo steroid acetate ester enol meroterpenoid methyl ester Show first 5 Terms
has_role: EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite

EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite Show first 5 Terms
inverse has_functional_parent: andrastin B

andrastin B Show first 5 Terms
inverse is_conjugate_base_of: andrastin C(1-)

andrastin C(1-) Show first 5 Terms
is_conjugate_acid_of: andrastin C(1-)

andrastin C(1-) Show first 5 Terms

Phenotype

Phenotype resulting from andrastin C

Phenotype where environments contain andrastin C

Phenotype modified by environments containing andrastin C

Human Disease Model